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Experiment details for aldh1a2Increased XRALDH2 activity has a posteriorizing effect on the central nervous system of Xenopus embryos.
Increased XRALDH2 activity has a posteriorizing effect on the central nervous system of Xenopus embryos.
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|Fig. 3. ATRA down-regulates XRALDH2 expression. (a,c) Control; and (b,d), 0.18 μM ATRA treated embryos were probed with XRALDH2 antisense RNA. Nieuwkoop–Faber stages of embryogenesis are indicated in the lower right corner of each picture (Nieuwkoop and Faber, 1967). (a,b) Anterior view (top, dorsal; bottom, ventral), the red arrow indicates the ablation of the XRALDH2 expression domain in stomodeal–hypophyseal, olfactory and eye anlagen; (c,d), lateral view (left, head; right, tail).|