| |
FIG. 3. Dorsal expression of VoxG4A does not induce expanded BMP-4 expression. Vegetal views of stage 12 embryos hybridized with an
antisense probe for BMP-4. Embryos were uninjected (A) or injected dorsally with 4 ng Vox (B) or 4 ng VoxG4A (C). (A) In uninjected
controls, BMP-4 expression is strongest adjacent to the ventral blastopore. This region of strong BMP-4 expression usually does not extend
more than halfway around the embryo. (B) BMP-4 expression is expanded dorsally and is often radial (as shown here) in embryos injected
dorsally with Vox (n 5 9). (C) BMP-4 expression is similar to controls in VoxG4A-injected embryos, showing a large area of dorsal clearing
(n 5 9). Arrowheads in A and C indicate the lateral edges of BMP-4 expression. |
