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bmp4xenopus hindgut [+] 

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Experiment details for bmp4

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs.

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs.

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Gene Clone Species Stages Anatomy
bmp4.L laevis NF stage 12 to NF stage 20 hindgut

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  Fig. S6: BMP/Smad1 and Wnt/β-catenin crosstalk. (A) Overlap between BMP-regulated/Smad1-bound and Wnt-regulated/β-catenin-bound genes. (B) Browser view of β-catenin and Smad1 peaks in Xenopus and human genes (from GSM1505734 and GSM1579346). Red boxes indicate overlapping Smad1 and β-catenin peaks. Black boxes indicate syntenic peaks. (C) In situ hybridization of DMH1, Tg(hsp70:dkk1) and BIO treated embryos in mid-sagittal section, anterior left and dorsal up. Embryos are either stage NF12 wild-type or treated at stage NF11 and fixed at stage NF20. * indicates hhex-expressing FG cells. (D) Expression heatmap of BMP and Wnt ligands and targets present in FG and HG samples of controls (CO), DMH1, Tg(hsp70:dkk1) and BIO-treated embryos.
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