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ephb1xenopus hindbrain 

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Experiment details for ephb1

The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis.

The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis.

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Gene Clone Species Stages Anatomy
ephb1.S laevis NF stage 33 and 34 hindbrain

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  Fig. 1. Expression of Xenopus EphB4 in the embryonic vasculature. Transcripts for EphB4 (A,B), Msr (C), EphB1 (D), EphB2 (E), and EphB3 (F) were detected by whole-mount in situ hybridization of stage 34 (A,C-F) and 36 (B) embryos. Lateral views are shown with anterior to the left. (A) Expression of EphB4 in the pronephric sinus (arrow) and the posterior cardinal vein (arrowheads) of the embryonic trunk. (B) Close-up view of the trunk region to illustrate EphB4 expression in the intersomitic veins (arrows), the vascular vitelline vein network (arrowhead), the pronephric sinus (ps) and the posterior cardinal vein (pcv). (C) Staining with the vascular marker Msr visualizes the vascular vitelline network (vvn), the common cardinal vein (ccv), pronephric sinus (ps), the posterior cardinal vein (pcv), and the intersomitic veins (iv). (D-F) EphB1, EphB2 and EphB3 transcripts are prominently detected in the head (fb, forebrain; mb, midbrain; e, eye; ov, otic vesicle; hm, head mesenchyme), in specific visceral arches (v1, v4), the cement gland (cg), and the pronephric region (pr), but not in intersomitic veins. Scale bars: 500 mm (A,C-D); 200 mm (B).
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