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fzd7xenopus   

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Experiment details for fzd7

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo.

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo.

Gene Clone Species Stages Anatomy
fzd7.L laevis NF stage 12 ectoderm , dorsal , presumptive paraxial mesoderm

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  Fig. 4. Geminin promotes expression of genes that mark pluripotent ectoderm and neurectoderm. Left: in situ hybridization of Geminin-overexpressing or MO knockdown embryos with injected area marked by Red-gal (Zic2/Fzd7/Sox2-MO/Sox3-Geminin) or X-gal (yellow arrowhead). Right: genes were assayed by qRT-PCR for changes in expression in stage 12 ectoderm and comparison of Geminin FL versus δcoil after Fig. 3.