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Experiment details for hhexAppl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells.
Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells.
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|Supp. Fig. S4. Dose-dependent inhibition of pancreas and SD marker gene expression in Xenopus embryos upon Wortmannin treatment. The embryos were treated with DMSO or 100–400 nM of Wortmannin from stages 30–42 and were subjected to whole mount in situ hybridization analysis at stage 42. Note that the duodenum expression domain of Foxa1 was nearly lost in 400-nM Wortmannin-treated embryos.|