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Figure 2. Xenopus orthologue of the hairy related gene (XHey-1) is expressed in the developing pronephric field in an overlapping pattern with other components of the Notch signaling pathway. The expression of Hey-1 is shown at stages 25 and 28 (A,F), and compared with both the expression of other components of the Notch signaling pathway (B-D,G-I) and with the pronephric anlage marker Lim-1 (E,J). Note that all four components of the Notch pathway shown here are expressed in an overlapping pattern, and this pattern is restricted to only the anterior-dorsal portion of the Lim-1 domain. This is the region of the pronephric anlage fated to contribute to the tubules. In all panels, embryos are viewed laterally with the anterior to the right. |
