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Experiment details for lhx1Kam RK et al. (2013) Assay
Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterning.
|Figure S2: dhrs3 suppresses the formation of pronephros. (A) The pronephros marker gene lhx1 indicated the position of the pronephros in stage 35 embryos. lhx1 was also expressed in the neural tube. (B) The expression of lhx1 in the pronephros region was enhanced by dhrs3 knockdown, suggesting that dhrs3 exerted an inhibitory role on pronephros development. (C) Overexpression of dhrs3 inhibited the development of pronephros, as showed by lhx1 staining in that region.|