|
Display additional annotations [+]
|
| |
Figure 2. Xenopus orthologue of the hairy related gene (XHey-1) is expressed in the developing pronephric field in an overlapping pattern with other components of the Notch signaling pathway. The expression of Hey-1 is shown at stages 25 and 28 (A,F), and compared with both the expression of other components of the Notch signaling pathway (B-D,G-I) and with the pronephric anlage marker Lim-1 (E,J). Note that all four components of the Notch pathway shown here are expressed in an overlapping pattern, and this pattern is restricted to only the anterior-dorsal portion of the Lim-1 domain. This is the region of the pronephric anlage fated to contribute to the tubules. In all panels, embryos are viewed laterally with the anterior to the right. |
|
Display additional annotations [+]
| Gene |
Clone |
Species |
Stages |
Anatomy |
|
jag1
|
|
laevis
|
NF stage 32
to
NF stage 35 and 36
|
brain
,
forebrain
,
midbrain
,
spinal cord
,
heart
,
[+]
|
|
jag1
|
|
laevis
|
NF stage 33 and 34
|
otic vesicle
,
brain
,
forebrain
,
midbrain
,
hindbrain
,
[+]
|
|
hey1
|
|
laevis
|
NF stage 32
to
NF stage 35 and 36
|
somite
,
heart
,
branchial arch
,
eye
,
head
|
|
| |
Figure 3. Later expression of the Xenopus orthologue of the hairy related gene (XHey-1) in comparison to Notch-1 and Serrate-1. XHey-1 expression persists in the somites (red arrows), head, eyes, and branchial arches of tadpole stage embryos shown from stages 32 to 35 (C,F,I). At this time, XHey-1 is also expressed in the heart (black arrows). Expression of Notch-1 and Serrate-1 is shown for comparison (A,B,D,E,G,H). Note that XHey-1 is expressed in a pattern largely overlapping that of Notch-1 and Serrate-1 in many tissues. However, unlike XHey-1, Notch-1, and Serrate-1 are expressed in the developing pronephros at this time (yellow arrows). In all panels, embryos are viewed laterally, with anterior to the right. |
