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otx2xenopus   

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Experiment details for otx2

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus.

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus.

Gene Clone Species Stages Anatomy
otx2.L laevis NF stage 17 pre-chordal neural plate , eye primordium , anterior placodal area
otx2.L laevis NF stage 29 and 30 forebrain , telencephalon , diencephalon , midbrain , eye , [+]

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  Fig. 5. MD3 KD affects early eye-field formation. Eye-field specification was analysed by WISH against the eye markers Rx1, Pax6, Otx2 in neurulas (stage 17; anterior view; A,A′,C,C′,E,E′) and tailbuds (stage 30; B,B′,D,D′,F,F′) injected with CT or MD3 MOs. Black dotted line, midline of embryo; arrowhead, enlarged (A′,C′,E′) and reduced (B′,D′,F′) expression domain of the eye markers; red asterisks, injected side of the embryo; numbers indicate the embryos analysed. Scale bar: 500 µm.