|
Display additional annotations [+]
|
| |
Fig. 2. Spemann's organizer is an early target of EtOH. Organizer-specific gene expression was studied in EtOH-treated embryos. Control (A, C, E, G, I) and EtOH-treated (B, D, F, H, J) embryos were analyzed for organizer specific gene expression at st. 10.5. The expression of chordin (A, B), gsc (C, D), Otx2 (E, F), Xnot2 (G, H) and Xbra (I, J) in EtOH-treated embryos is shown. |
|
Display additional annotations [+]
|
| |
Fig. 6. Citral affects organizer-specific gene expression. In order to reduce the endogenous RA levels, embryos were treated with citral (60 μM). The embryos were processed for in situ hybridization with gsc (A, B), Otx2 (C, D), chordin (E, F) and Xnot2 (G, H) specific probes. Control untreated sibling embryos are marked. |
|
Display additional annotations [+]
|
| |
Fig. 7. RA metabolism by Cyp26 overexpression results in changes in organizer-specific gene expression. Active RA levels were reduced by Cyp26 mRNA injection. At st. 10.5, the embryos were processed for in situ hybridization with chordin (A, B) and Otx2 (C, D) specific probes. Control untreated sibling embryos are marked. |
