| |
Figure 1. Expression patterns of p2ry4 during early development. WISH of p2ry4 from gastrula to tailbud stage. Stages 10.5 and 11 (a and c, dorsal views; b and d, sagittal hemisections). p2ry4 was expressed in the prospective neuroectoderm and the involuting dorsal and ventral mesoderm at gastrula stage. At stage 10.5, p2ry4 was prominently expressed in the head organizer region (b). Stages 13, 17, 19, and 21 (e, f, h, j, anterior views; k, dorsal view; g, sagittal hemisection; i, transverse section). Stage 28 (l, lateral view; m, transverse section; m’, high‐magnification image of m). The extirpated brain of tadpole (n, lateral side; o, dorsal side). nc, neural crest; pl, placode cell; anp, anterior neural plate; mhb, midbrain‐hindbrain boundary; nt, neural tube; not, notochord; som, somite; cg, cement gland; tel, telencephalon; di, diencephalon; mes, mesencephalon; met, metencephalon. Dotted straight line indicates section plane. Black arrowheads indicate blastopore |
