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Gene/Clone	Species	Stage	Anatomy Item	Experimenter
pax2	xenopus

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Experiment details for pax2

Retinoic acid is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus laevis.

Retinoic acid is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus laevis.

Gene	Clone	Species	Stages	Anatomy
pax2.L		laevis	NF stage 29 and 30	brain , forebrain , telencephalon , hindbrain , midbrain-hindbrain boundary , [+] neuroectoderm , pharyngeal arch , posterior neural tube , pronephric mesenchyme , neural tube , olfactory bulb
pax2.L		laevis	NF stage 32	brain , hindbrain , midbrain-hindbrain boundary , neuroectoderm , pronephric duct , [+] posterior neural tube , pronephric nephron , pronephric kidney , neural tube
pax2.L		laevis	NF stage 32	otic vesicle , brain , forebrain , telencephalon , hindbrain , [+] midbrain-hindbrain boundary , head region , pronephric duct , thyroid , posterior neural tube , pronephric nephron , early distal tubule , pronephric kidney , neural tube , olfactory bulb
pax2.L		laevis	NF stage 33 and 34 to NF stage 40	brain , forebrain , telencephalon , hindbrain , midbrain-hindbrain boundary , [+] pronephric duct , endoderm , thyroid , posterior neural tube , pronephric nephron , early distal tubule , pronephric kidney , neural tube , hypothalamus

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Figure 1. Temporal expression of lung and thyroid markers. Whole mount in situ hybridization was used to compare the temporal expression of key early genes in the development of the thyroid and lung. Expression of nkx2.1 is first detectable in the thyroid (red arrows) at stage 30 and is subsequently expressed in the lung (green arrows) at stage 34. Expression of pax2 begins at stage 32 in the thyroid. Expression of the differentiation markers sftpb and sftpc is first detectable at stage 38.