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pax6xenopus   

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Experiment details for pax6

Nabeshima A et al. (2013) Assay

Loss of cell-extracellular matrix interaction triggers retinal regeneration accompanied by Rax and Pax6 activation.

Gene Clone Species Stages Anatomy
pax6.L laevis NF stage 35 and 36 lens , retina , diencephalon , eye

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  FIG. 1. Expression of the Rax gene in the transgenic Xenopus F0 founder. A, B: In situ hybridization of the Rax gene in Xenopus embryos at St. 35. In both whole mount and section preparations, Rax was expressed specifically in the neural retina. C, D: Pax6 is also expressed similarly to Rax at this stage of development. E: EGFP expression in transgenic animals at St. 27 (E, F) and St. 31 (G, H). EGFP is local- ized only in the eye region. In H, the neural retina is intensely stained for EGFP and the lens is devoid of staining.