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Figure 2. Syndecan-2 in Animal Cap Cells Functions Early in Left-Right DevelopmentRepresentative in situ hybridizations of nodal (top row, stage 24 embryos; uninjected, n = 22; δS2 treated, n = 65) and lefty (middle row, stage 24; uninjected, n = 16; δS2 treated, n = 61) in the lateral plate mesoderm or pitx2 (bottom row, stage 26; uninjected, n = 18; δS2 treated, n = 30) in the heart field. The frequency of the observed expression pattern for each marker is indicated with each panel. Panels in the top two rows (nodal and lefty) are dorsal views, and those in the bottom row are ventral views; anterior is at the top. |