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pitx2xenopus   

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Experiment details for pitx2

The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum.

The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum.

Gene Clone Species Stages Anatomy
pitx2.L laevis NF stage 35 and 36 mesoderm

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  Fig. 4. Asymmetric expression of pitx2 during Xenopus liver morphogenesis.In situ hybridization was performed on whole NF 35 embryos (A-B) or on serial sections (C-D),probing for the liver specific transcription factor, hhex (A, C), or the LR determinant , pitx2 (B, D). Dotted line in A approximates the section planes shown in C and D. The expression of pitx2is confined to the mesoderm surrounding the left side of the liver diverticulum (arrows in B, D). R=right, L=left. Scale bars= 200 μm.