|runx1t1||xenopus||presumptive midbrain-hindbrain boundary [+]|
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Experiment details for runx1t1Oropez D and Horb M (2012) Assay
Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells.
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|Figure 8. Validation of microarray data. Following 4 h of Ngn3-GR activation at Stage 12 candidate genes from the microarray analysis were increased in the endoderm at Stage 15: (a,b) tbx2 (n = 24/24). (c,d) mtg8 (n = 21/21). (e,f) hes3 (n = 14/42). (g,h) geminin (n = 13/44). (i,j) oct25 (n = 13/13). And at Stage 20: (k,l) mtgr1 (n = 9/13). Dashed circles and arrows indicate ectopic expression in the anterior endoderm. Dashed line indicates ectopic expression in the dorsal endoderm.|