Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Search Criteria
Gene/CloneSpeciesStageAnatomy ItemExperimenter
six1xenopus   

Too many results?Too few results?

Experiment details for six1

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes.

Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes.

Gene Clone Species Stages Anatomy
six1.L laevis NF stage 17 trigeminal placode , profundal placode , anterior placodal area
six1.L laevis NF stage 24 olfactory placode , otic vesicle , epibranchial placode , facial epibranchial placode , glossopharyngeal epibranchial placode , [+]
six1.L laevis NF stage 28 olfactory placode , otic vesicle , epibranchial placode , facial epibranchial placode , glossopharyngeal epibranchial placode , [+]

Display additional annotations [+]
  Figure 4—figure supplement 2. Expression of targets that broadly overlap with PPE in whole-mount Xenopus embryos. Expression dynamics for each target are shown across a range of developmental stages: A1–E1 show expression in neural plate stage embryos, A2–E2 show early tail bud stage embryos and A3–E3 show late tail bud stage embryos. (A) Expression of PPE marker gene Six1 is shown as reference for placodal domains (for details see Pandur and Moody, 2000; Schlosser and Ahrens, 2004). (B) Crem is initially expressed broadly in paraxial mesoderm (B1; asterisk) and cranial ectoderm (B1; arrowhead) at neural plate stages and in pharyngeal arches and overlying ectoderm at early and late tail bud stages (B2 and B3 ; diamond). (C) FosB is expressed in a broad pattern across the cranial ectoderm and trunk mesoderm at both neural fold and early tail bud stages (C1 and C2). At late tail bud stages expression is maintained in cranial ectoderm as well as becoming apparent in the migrating neural crest cells (Nc) and weakly in the somites (C3; arrowhead). (D) Znf214 is expressed broadly across the ectoderm at all developmental stages (D1–D3). At both early and late tail bud stages there is expression in the migrating neural crest cells (Nc) as well as in the retina (D2 and D3; asterisk), and in late tail bud stages Znf214 is expressed in the otic vesicle and lens. (E) Ripply3 is expressed broadly in the posterior placodal region at neural fold stages (E1). At both early and late tail bud stages expression is confined to posterior cranial ectoderm (E2 and E3; asterisk). Yellow arrows mark placodal expression. Abbreviations: pA: anterior placodal region; pAD: anterior lateral line placode; pE: epibranchial placode; L: lens; pM: middle lateral line placode; pO: olfactory placode; vOt: otic vesicle; pP: posterior placodal region; pPrV: profundal/trigeminal placodes.