|
Gene |
Clone |
Species |
Stages |
Anatomy |
sox9.S
|
|
laevis
|
NF stage 26
to
NF stage 32
|
otic vesicle
,
brain
,
mandibular crest
,
hyoid crest
,
branchial crest
,
[+]
|
sox9.S
|
|
laevis
|
NF stage 35 and 36
|
otic vesicle
,
brain
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
[+]
|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
isl1
|
|
laevis
|
NF stage 28
|
olfactory placode
,
pineal gland
,
epibranchial placode
,
profundus ganglion
,
trigeminal ganglion
,
[+]
|
pmp22
|
|
laevis
|
NF stage 15
|
cement gland primordium
,
paraxial mesoderm
|
pmp22
|
|
laevis
|
NF stage 26
|
presomitic mesoderm
,
somite
,
trigeminal ganglion
,
profundal placode
,
caudal presomitic mesoderm
|
pmp22
|
|
laevis
|
NF stage 28
|
presomitic mesoderm
,
somite
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
[+]
|
pmp22
|
|
laevis
|
NF stage 35 and 36
|
somite
,
pharyngeal arch
,
head
,
tail somite
|
|
|
Fig. 2. Expression of Pmp22 in whole-mount in situ hybridization. (A) Expression of Pmp22 at stage 15 in the cement gland. Anterior view, dorsal to top. (B) At stage 22,
Pmp22 was detected in the developing somites and profundal and trigeminal nerves. (C) At stage 22 Pmp22 sense probe was used as a negative control. (D) Pmp22 was
expressed in the profundal and trigeminal ganglia, cranial mesenchyme, and somites at stage 29/30, where it was also beginning to be expressed in the branchial arches.
(E) Strong expression of Pmp22 was observed in the craniofacial region. (F–G, I) To confirm the tissue-specific expression of Pmp22, we also performed in situ hybridization
for Sox9 and Islet1. (H, I) At stage 35, both Pmp22 and Sox9 were detected in the branchial arches. Panels (B–I), lateral view, anterior to the left. ba, branchial arches; cg,
cement gland; pr, profundal ganglia; s, somites; tg, trigeminal ganglia. |