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sulf2xenopus anterior 

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Experiment details for sulf2

Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2.

Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2.

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Gene Clone Species Stages Anatomy
sulf2 tropicalis NF stage 20 anterior

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  Fig. 1. Zygotic expression of XtSulf2. Zygotic transcripts for XtSulf2 are detected by whole mount in situ hybridisation in X. tropicalis embryos. (A–B) At stage 18, zygotic transcripts for XtSulf2 are detected in the anterior neural tube most promimently at the mid-hindbrain junction (asterisk in B). (C–D) At stage 20, XtSulf2 is expressed in the ventral part of anterior neural tube, in the ventral midbrain and hindbrain and at the midbrain–hindbrain junction (asterisk), and in the mandibular mesendoderm underlying the presumptive cement gland (arrow in D and E). (E) At stage 25, XtSulf2 is expressed in the pineal gland (arrowhead), the mandibular mesendoderm subjacent to the cement gland (arrow), the MHJ (asterisk) and the pineal gland (arrowhead). Strong expression continues in the ventral midbrain and hindbrain. (F–J) At stage 28, XtSulf2 is expressed in the mandibular arch, pineal gland and neural retina. Expression is detected in the ventricular zone (VZ) of the midbrain and ventrally in the neural tube. (K) At stage 35, XtSulf2 is expressed in the MHJ (asterisk), pineal gland (arrowhead) olfactory placodes (arrows), and neural retina. (G–J, L–O) 50 µm vibratome transverse sections through respectively (F) and (K). (G, I, L, N) 10× magnification, (H, J, M, O) 40× magnification. R is retina, VZ is ventricular zone, NT is neural tube, and Nc is notochord.