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tbx5xenopus   

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Experiment details for tbx5

Cardiac neural crest is dispensable for outflow tract septation in Xenopus.

Cardiac neural crest is dispensable for outflow tract septation in Xenopus.

Gene Clone Species Stages Anatomy
tbx5.S laevis NF stage 25 to NF stage 29 and 30 retina , heart , myocardium , cardiac mesoderm , heart primordium , [+]
tbx5.S laevis NF stage 33 and 34 to NF stage 35 and 36 retina , heart , myocardium , cardiac ventricle

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  Fig. 3. Molecular characterization of the primary and second heart fields. (A-U) Developmental expression of Nkx2.5, Tbx5 and Tbx20 at stages 25, 30, 33 and 35 as indicated. The horizontal lines indicate the predicted position of primary heart field (PHF) and second heart field (SHF). All three genes are detected in the PHF, whereas the SHF expresses both Nkx2.5 and Tbx20 but is negative for Tbx5 expression. At later stages, the developing outflow tract (OFT), a derivative of the SHF, remains Tbx5 negative. (A,C,E,G,I,K,M-U) Lateral views, anterior to right. (B,D,F,H,J,L) Ventral views, anterior to top. V, ventricle. Scale bars: 100 μm.