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Fig. 5. Neural crest segregation and migration in XHoxa2- injected embryos. (A,B) Lateral views of a whole-mount stage 18 embryo hybridised with XSlug. (A) Pre-migratory NC blocks are clearly segregated on the uninjected side (arrows), though not on the injected side (B, asterisks). (C-E) Lateral views of stage 28 embryos hybridized with XAP-2 showing mild (D) and severe (E) alterations in NC stream segregation and migration, as compared with wild type (C). BCS, branchial crest segment; CG, cement gland; E, eye; HCS, hyoid crest segment; MCS, mandibular crest segment; PA, pharyngeal arch. |