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abl2xenopus neuroectoderm [+] 

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Experiment details for abl2

Bonacci G et al. (2012) Assay

The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization.

Gene Clone Species Stages Anatomy
abl2.L laevis NF stage 10.25 neuroectoderm
abl2.L laevis NF stage 11 neuroectoderm
abl2.L laevis NF stage 17 neuroectoderm
abl2.L laevis NF stage 22 neural tube , neural fold , brain
abl2.L laevis NF stage 28 brain

  Fig. 1. Expression of Arg during early Xenopus development. A) Schematic representation of sequence alignment between human and Xenopus Arg proteins. The SH2, SH3 and tyrosine kinase domains are over 92% identical, while the actin binding domains (BDs) are 74–76% identical between the two proteins. B) Temporal expression of Arg assayed by RT-PCR (25 cycles) showed that Arg was expressed maternally and its transcripts persisted till at least tailbud stages. C) Spatial expression of Arg assayed by in situ hybridization of gastrula (panels a and b), neurula (panel c), tailbud (panels d and e) and early tadpole (panel f) embryos. The orientations of the embryos are: panel a, side view with dorsal to the right; panel b, vegetal view with dorsal to the right; panels c and e, dorsal view with anterior to the left; panels d and f, side view with anterior to the left.

Gene Clone Species Stages Anatomy
abl2.L laevis NF stage 10.25 neuroectoderm

  abl2 (ABL proto-oncogene 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 10, dorsal right, animal hemisphere up.

Gene Clone Species Stages Anatomy
abl2.L laevis NF stage 11 neuroectoderm

  abl2 (ABL proto-oncogene 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 11, vegetal view, dorsal right.

Gene Clone Species Stages Anatomy
abl2.L laevis NF stage 17 neuroectoderm

  abl2 (ABL proto-oncogene 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 17, dorsal view, anterior left.

Gene Clone Species Stages Anatomy
abl2.L laevis NF stage 22 brain

  abl2 (ABL proto-oncogene 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 22, lateral view, anterior left, dorsal up.

Gene Clone Species Stages Anatomy
abl2.L laevis NF stage 22 neural tube , neural fold , brain

  abl2 (ABL proto-oncogene 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 22, dorsal view, anterior left.

Gene Clone Species Stages Anatomy
abl2.L laevis NF stage 28 brain

  abl2 (ABL proto-oncogene 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 11, lateral view, anterior left, dorsal up.