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Gene/CloneSpeciesStageAnatomy ItemExperimenter
c12orf43xenopus dorsolateral neural tube 

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Experiment details for c1h12orf43

Custos controls β-catenin to regulate head development during vertebrate embryogenesis.

Custos controls β-catenin to regulate head development during vertebrate embryogenesis.

Gene Clone Species Stages Anatomy
c1h12orf43.L laevis NF stage 23 dorsolateral neural tube

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  Fig. S4. Temporal and spatial expression pattern of Custos in Xenopus embryo. (A) Xenopus Custos is expressed throughout development. The expression level of Custos RNA was assessed by RT-PCR analysis. Ornithine Decarboxylase (ODC) was used as an internal control, RT(−) is without reverse transcriptase as a negative control. (B) Custos is highly expressed in the anterior region of the embryo. Whole-mount in situ hybridization was performed using a Xenopus Custos anti-sense RNA probe. No signal was detected using a Custos sense RNA probe. (C) Expression of Custos does not induce or suppress levels of activated RhoA in HEK-293T cells; the GEF Ephexin is used as a positive control. (D) Sequence of Xenopus Custos antisense morpholino oligonucleotide (MO) is indicated by red letters.