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Figure 1 Spatial expression of prmt4 [carm1]
A: Lateral view of a stage 10 embryo with dorsal toward the left showing differential expression of prmt4 along the dorsoventral axis. Arrow indicates signal on the dorsal side.
B–F: prmt4 signal detected in the neural crest and neural plate border during the neurula stage. B: Stage 15 embryo; C, D: Stage 18 embryos;
E, F: Stage 20 embryos. B, C, E: Dorsal view with anterior toward the top. D, F: Anterior view with dorsal toward the top.
G–L: Expression of prmt4 detected in the brain, spinal cord, branchial arches, and heart anlage. G, H, J, K: Lateral view of stage 25 (G), stage 28 (H), stage 35 (J), and stage 40 (K) embryos. Enlarged head regions of embryos in J and K are shown in I and L, respectively.
M: Transverse section of embryo at the level illustrated by the black line in C. N: Longitudinal section of a stage 40 embryo. O–R: Transverse sections of embryo at the levels illustrated by the black lines in K.
ba: branchial arches; e: eye; en:endoderm; ch: second pharyngeal arch; h: heart; m: first pharyngeal (maxillary) arch; msz: marginal and subventricular zones of midbrain and neural tube; nc:
neural crest; np: neural plate; nt: neural tube; op: olfactory placode; pa: pharyngeal arch; pm: paraxial mesoderm; sc: spinal cord; vz: ventricular zone of neural tube. |
