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Fig. 4.
Expression patterns of BMP pathway target genes are affected by the homozygous nogRMH3 mutanion in a stage specific manner. (A–D) Expression of msx1 in the head of representative WT (A,C) and homozygous nogRMH3 (B,D) tadpoles. (E–H) Expression of msx2 in the head of representative WT (E,G) and homozygous nogRMH3 (F,H) tadpoles. (I–L) Expression of edn1 in the head of representative WT (I,K) and homozygous nogRMH3 (J,L) tadpoles. (M–P) Expression of dlx1 in the head of representative WT (M,O) and homozygous nogRMH3 (N,P) tadpoles. (A–B,E–F,I–J,M–N) Stage 33. (C–D,G–H,K–L,O–P) Stage 38. Anterior to the left and dorsal towards the top. (A,C,E,G,I,K,M,O) Arrows show domains of expression of indicated genes in WT tadpoles. (B,D,F,H,J,L,N,P) Arrowheads show altered expression domains in homozygous nogRMH3 mutants.
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