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ednrb2 (endothelin receptor B subtype 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 28, lateral view, anterior right, dorsal up. |
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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
mitf
|
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laevis
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NF stage 19
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neural crest
,
trunk neural crest
,
melanoblast
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dct
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laevis
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NF stage 25
to
NF stage 28
|
neural crest
,
trunk region
,
melanoblast
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dct
|
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laevis
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NF stage 32
to
NF stage 35 and 36
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retina
,
pineal gland
,
neural tube
,
retinal pigmented epithelium
,
melanoblast
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dct
|
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laevis
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NF stage 39
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retina
,
hindbrain
,
head region
,
pineal gland
,
eye
,
[+]
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ednrb2
|
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laevis
|
NF stage 21
to
NF stage 25
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roof plate
,
head region
,
neural crest
,
trunk region
,
neural tube
,
[+]
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ednrb2
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laevis
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NF stage 28
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head region
,
trunk region
,
trunk neural crest
,
neural tube
,
migratory neural crest cell
,
[+]
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Fig. 1. Ednrb2 and melanoblast marker gene expression patterns in Xenopus embryos by WISH. A,B: Mitf expression is detected (A), but there is no Ednrb2 expression in a stage-19 embryo. C: Ednrb2 expression (arrowheads) is first detected in the NT at stage 21. D–F: Weak Dct (D) and strong Ednrb2 (E,F) expression is detected at stage 25. G–I: Dct (G) and Ednrb2 (H,I) expression is detected in the NT and only Ednrb2 is expressed in the head region at stage 28 (red arrowheads). J–R: The expression pattern of Ednrb2 (K,O,R) resembles that of Dct (J,M,P) except in the RPE (Dct only). Blue arrowheads indicate expression in the epiphysis. Note that after stage 35, melanophores are pigmented, but because the embryos are bleached in these embryos, the melanins are not visible. Insets are magnified images in the squares (scale bar ¼ 100 mm) and show dendritic pigmented melanophores expressing both Dct (P) and Ednrb2 (R). F, I, L, O, and R are lateral views of E, H, K, N, and Q, respectively. Heads are on the right side of each picture. Scale bar ¼ 1 mm. |
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ednrb2 (endothelin receptor B subtype 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 32, lateral view, anterior right, dorsal up. |
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ednrb2 (endothelin receptor B subtype 2) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 35 & 36, lateral view, anterior right, dorsal up. |