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Fig. 1. Developmental patterns of elrC and elrD expressions. Whole mount in situ hybridizations of elrC (A±G) and elrD (H±K). (A) Stage 12, dorsal view: elrC is expressed in longitudinal stripes (arrows), parallel to the anterior posterior axis, corresponding to primary neurons. (B) Stage 14, dorsal view. The primary neurons (arrows) and the trigeminal placodes (arrowhead) are labeled. Stage 17, dorsal (C) and anterior (D) views: the neural tube (arrow), the trigeminal placodes (arrowhead) and the olfactory placodes (red arrow) are labeled. Stage 20, dorsal (E) and anterior (F) views: in addition to the neural tube (arrow) and the olfactory placodes (red arrow), the developing cranial ganglia (arrowhead) are also labeled. (G) Stage 32, lateral view: elrC transcripts accumulate in the spinal cord, the brain and the cranial ganglia (arrowheads). Stages 17 (H) and 20 (I), dorsal views: elrD expression is detected in the neural tube (arrow). (J) Stage 20, anterior view. The neural tube (arrow), the trigeminal placode (arrowhead) and the olfactory placodes (red arrow) are labeled. (K) Stage 32, lateral view: elrD transcripts are found in the spinal cord, the brain and the cranial ganglia (arrowheads). In all dorsal views anterior is to the right. After whole mount in situ hybridization of elrC (L) or elrD (M), stage 18 embryos were sectioned. Expression of elrC and elrD in the neural tube are similar. Scale bar, (A±K) 300 um, (L,M) 60 um. |
