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gscxenopus branchial arch 

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Experiment details for gsc

Griffin JN et al. (2015) Assay

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus.

Gene Clone Species Stages Anatomy
gsc tropicalis NF stage 28 branchial arch

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  Fig 3. Knockdown of nol11 disrupts cranial neural crest development. At stages 14 and 24 neural and CNC development appears normal in one side treated embryos, as assayed by expression of key marker genes including sox3, cytokeratin, twist and slug. By stage 28 however, reductions are apparent in the expression of numerous CNC genes. The branchial arches are also smaller on the MO treated side at stage 28. Graph displays number of embryos exhibiting abnormal gene expression in control and nol11 morphant embryos. doi:10.1371/journal.pgen.1005018.g003