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leftyxenopus embryonic structure 

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Expression summary for lefty

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Experiment Species Images Stages Anatomy Assay
XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning.

Paper
laevis
1 image
NF stage 25 to NF stage 26 lateral plate mesoderm in situ hybridization
XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning.

Paper
laevis
1 image
NF stage 25 to NF stage 26 lateral plate mesoderm in situ hybridization
Ectodermal syndecan-2 mediates left-right axis formation in migrating mesoderm as a cell-nonautonomous Vg1 cofactor.

Paper
laevis
1 image
NF stage 24 lateral plate mesoderm in situ hybridization
Expression cloning of Xantivin, a Xenopus lefty/antivin-related gene, involved in the regulation of activin signaling during ...

Paper
laevis
1 image
NF stage 9 to NF stage 25 dorsal marginal zone, lateral plate mesoderm, upper blastopore lip in situ hybridization
Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation.

Paper
laevis
1 image
NF stage 10.5 blastopore lip, dorsal marginal zone, marginal zone in situ hybridization
Regulation of gut and heart left-right asymmetry by context-dependent interactions between xenopus lefty and BMP4 signaling.

Paper
laevis
1 image
NF stage 10 to NF stage 23 blastopore, lateral plate mesoderm, prechordal plate, vegetal yolk mass in situ hybridization
APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis.

Paper
laevis
1 image
NF stage 24 lateral plate mesoderm in situ hybridization
RFX2 is broadly required for ciliogenesis during vertebrate development.

Paper
laevis
1 image
NF stage 26 heart primordium in situ hybridization
E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation.

Paper
laevis
1 image
NF stage 11 dorsal marginal zone, marginal zone in situ hybridization
Wills AE and Baker JC (2015) Assay

Paper
laevis
1 image
NF stage 10 dorsal marginal zone, marginal zone in situ hybridization
Coordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during...

Paper
laevis
1 image
NF stage 27 lateral plate mesoderm in situ hybridization
HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a nodal and lefty a...

Paper
laevis
1 image
NF stage 23 lateral plate mesoderm in situ hybridization

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