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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
lzts2
|
|
laevis
|
NF stage 11
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mesoderm
,
lateral
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lzts2
|
|
laevis
|
NF stage 13
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dorsal
|
lzts2
|
|
laevis
|
NF stage 17
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somite
|
lzts2
|
|
laevis
|
NF stage 23
|
forebrain
,
midbrain-hindbrain boundary
,
proctodeum
|
lzts2
|
|
laevis
|
NF stage 27
|
midbrain-hindbrain boundary
,
somite
,
trigeminal ganglion
,
pronephric kidney
,
pronephric tubule
|
lzts2
|
|
laevis
|
NF stage 32
|
forebrain
,
somite
,
mesonephric collecting duct
,
trigeminal ganglion
,
pronephric kidney
,
[+]
|
lzts2
|
|
laevis
|
NF stage 40
|
head mesoderm
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Figure 5. Spatio-temporal expression of LAPSER1 during X. laevis development. A: Ventral view of an embryo at stage 11. LAPSER1 is expressed in the migrating meso-ectoderm (white arrow). B: Dorsal view of an embryo at stage 13. Posterior is to the top. A faint LAPSER1 expression can be seen in the dorsal part of the embryo. C: Dorsal view of an embryo at stage 17, anterior orientated to the right. The blue arrow depicts LAPSER1 expression in the segmenting somites. D: Ventral view of a Xenopus tail. LAPSER1 transcripts can be detected in the proctodeum (green arrow). E: Anterior view of an embryo at stage 23. LAPSER1 can be visualized in the forebrain (red arrowheads). F–J: Lateral views of Xenopus embryo at indicated stages. F: LAPSER1 expression is shown in the somites that undergo segmentation (blue arrow). G: LAPSER1 is expressed in the isthmus (green arrowhead). Dotted lines indicate level of sections shown in L–Q. H: At stage 32, LAPSER1 is expressed in the posterior somites that undergo segmentation (blue arrow), the segmented somites (blue arrowhead), the pronephros (black arrow and arrowhead), and the trigeminal ganglion (gV). I: LAPSER1 is clearly expressed in some cranial ganglions as indicated. In addition, LAPSER1 transcripts are found in the proximal part of the pronephros (arrow) and slightly in the collecting tubule (arowhead). Dotted lines indicate level of sections shown in R and S. J: At stage 40, LAPSER1 expression is detected in the head mesenchyme (white arrowhead). K–M, R,S: Horizontal sections. N–Q: Transverse sections. K: LAPSER1 is strongly expressed in the somites undergoing segmentation. L: LAPSER1 transcripts can be detected in the segmenting and rotating somites (blue arrows). M: LAPSER1 is slightly expressed in the somites (blue arrow) and the trigeminal ganglion (gV). N: LAPSER1 can be visualized in the trigeminal ganglion (gV). O: LAPSER1 is expressed in the somites (blue arrowhead), the hypochord (yellow arrowhead), and the proximal pronephros anlage (black arrow). P: LAPSER1 is detectable in the forming collecting tubule of the pronephros. Q: LAPSER1 transcripts in the somites (arrow). R: LAPSER1 is expressed in the proximal tubule (arrow). S: LAPSER1 mRNA can be localized in diverse cranial ganglions as indicated. e, eye; egVII, facial epibranchial ganglion; egIX, glossopharyngeal epibranchial ganglion; epXI, first vagal epibranchial ganglion; gV, trigeminal ganglion; gVPL, cells that contribute to the vagal and posterior lateral line ganglion.Download figure to PowerPoint |
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lzts2 (leucine zipper, putative tumor suppressor 2 ) gene expression in Xenopus laevis embryos, NF stage 33 & 34, as assayed by in situ hybridization, lateral view: anterior right, dorsal up.
Key: egVII, facial epibranchial placode; egIX, glossopharyngeal epibranchial placode; epXI, first vagal epibranchial placode; gVPL, cells that contribute to the vagal and posterior lateral line placode |