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Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
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mxi1 | xenopus | stomodeal-hypophyseal primordium [+] |
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Experiment details for mxi1
Arima K et al. (2005) AssayGlobal analysis of RAR-responsive genes in the Xenopus neurula using cDNA microarrays.
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Fig. 5. The effects of modulated retinoid signaling on expression pattern of retinoic acid receptor (RAR) target genes. The effects of AGN 193109, TTNPB, or vehicle control on expression pattern of three expressed sequence tags (ESTs), XL016p20 (S1�S6), XL049b08 (T1�T6), and XL043c08 (U1�U6), were determined in stage 18 embryos by whole-mount in situ hybridization. AGN193109 treatment reduced posterior neural expression of all three genes compared with controls (S1 vs. S2, T1 vs. T2, and U1 vs. U2) but increased medial staining of XL016p20 (S1 vs. S2), XL049b08 staining in the eye anlagen (T4 vs. T5), and XL043C08 expression in the forebrain (U1 vs. U2). In contrast, TTNPB treatment increased expression of XL016P20 throughout the embryo (S3, S6 vs. S2, S5) and reduced Xl043C08 staining in the forebrain and presumptive trigeminal ganglion (U3, U6 vs. U2, U5). S1�S3, T1�T3, and U1�U3: dorsal view; S4�S6, T4�T6, and U4�U6: anterior view; TTNPB, TTNPB-treated embryos; Control, vehicle control embryo; AGN193109, AGN193109-treated embryos. |