|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
not
|
|
laevis
|
NF stage 14
|
pre-chordal neural plate
,
notochord
,
circumblastoporal collar
,
axial mesoderm
,
neural plate
,
[+]
|
foxd4l1.1
|
|
laevis
|
NF stage 10.5
to
NF stage 11
|
dorsal marginal zone
|
foxd4l1.1
|
|
laevis
|
NF stage 14
|
notochord
,
neural plate
,
floor plate
,
neural tube
|
foxa4
|
|
laevis
|
NF stage 10.5
to
NF stage 11
|
dorsal marginal zone
,
blastopore lip
|
foxa4
|
|
laevis
|
NF stage 14
|
notochord
,
neural plate
,
floor plate
,
neural tube
|
foxa1
|
|
laevis
|
NF stage 10.5
to
NF stage 11
|
dorsal marginal zone
,
presumptive axial mesoderm
|
foxa1
|
|
laevis
|
NF stage 14
|
notochord
,
axial mesoderm
,
neural groove
,
neural plate
,
floor plate
,
[+]
|
shh
|
|
laevis
|
NF stage 10.5
to
NF stage 11
|
mesoderm
,
dorsal marginal zone
,
upper blastopore lip
|
shh
|
|
laevis
|
NF stage 16
|
notochord
,
hypochord
,
neural groove
,
floor plate
,
neural tube
|
ntn1
|
|
laevis
|
NF stage 14
to
NF stage 16
|
pre-chordal neural plate
,
neural plate
,
floor plate
,
neural fold
|
enc1.2
|
|
laevis
|
NF stage 10.5
to
NF stage 11
|
dorsal marginal zone
,
upper blastopore lip
,
presumptive axial mesoderm
|
enc1.2
|
|
laevis
|
NF stage 14
|
pre-chordal neural plate
,
notochord
,
axial mesoderm
,
floor plate
,
neural tube
|
|
|
Fig. S6. Analysis of floor plate markers reveals two separate populations of medial floor plate.
In situ hybridization for indicated markers was performed at stage 10.5–11 (A, C, E, G, I, K, M) and neurula stages (st.14—B, D, F, J, L, N, O; st.16—H, P). Prime panels (B', etc.) show transverse bisections of matching neurula stages (notochord outlined in red). Markers expressed in the organizer (marked by asterisk) at gastrula stages are expressed throughout the dorsal midline and in a narrow domain in the floor plate (A–N') at neurula stages. Netrin expression begins at early neurula stages (st.14, O) in a wider domain than early markers (O', P' compared to B'–N'). We have designated the narrow, early-forming FP the 1° MFP and the wider, later-forming FP the 2° FP. |