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Search Criteria

Gene/Clone	Species	Stage	Anatomy Item	Experimenter
pitx2	xenopus		lateral plate mesoderm [+] somatic layer of lateral plate mesoderm,splanchnic layer of lateral plate mesoderm,external carotid artery,filter chamber,anterior dorsal lateral plate region,hematopoietic stem cell,ventral mesoderm,dorsal lateral plate mesoderm,anterior palatine artery,anterior ventral blood island,cerebral artery,distal tubule,early distal tubule,early proximal tubule,endothelial cell,gamete,glomeral nexus,glomerular epithelial cell,glomerular mesangial cell,glomerulus,glomus,hematopoietic stem cell,late distal tubule,late proximal tubule,macrophage,mesonephric collecting duct,mesonephric tubule,migrating macrophage,neutrophil,ophthalmic artery,podocyte,posterior palatine artery,posterior ventral blood island,pronephric duct,pronephric nephron,pronephric nephrostome,pronephric sinus,pronephric tubule,proximal tubule,proximal tubule branch,smooth muscle myocyte,thrombocyte,ventral blood island border,Mullerian duct,adult thrombocyte,anterior cardinal vein,anterior lymph sac,anterior palatine artery,anterior ventral blood island,arteria iliaca communis,arteria mesenterica posterior,arteria subclavia,arterial endothelium,blood,capillary system of liver,cardinal vein,caudal artery,caudal vein,cerebral artery,coeliaco-mesenteric artery,coelomic epithelium,dorsal aorta,dorsal lymph space,duct of Cuvier,erythroid cell,external jugular vein,gastric vein,genital ridge,genital system,glomeral mesenchyme,glomeral nexus,glomus,hepatic portal vein,hepatic vein,intermediate mesoderm,internal carotid artery,internal jugular vein,interrenal vein,intersomitic artery,intersomitic vein,kidney,larval aorta,lateral postcardinal vein,left lymph heart,left spleen primordium,lymph vessel,medial abdominal vein,medial cardinal vein,mesonephric duct,mesonephric early distal tubule,mesonephric early proximal tubule,mesonephric late distal tubule,mesonephric late proximal tubule,mesonephric mesenchyme,mesonephric nephron,mesonephric sinus,migrating macrophage,musculoabdominal vein,myeloid cell,occipitovertebral artery,omphalomesenteric vein,oviduct,paired dorsal aorta,posterior cardinal vein,posterior vena cava,posterior ventral blood island,pronephric duct,pronephric kidney,pronephric mesenchyme,pronephric nephrostome,pronephric sinus,pulmonary vein,right lymph heart,right spleen primordium,smooth muscle,somatic layer of lateral plate mesoderm,splanchnic layer of lateral plate mesoderm,spleen,subinterstitial vein,tail vein,thrombocyte,vascular endothelium,venous endothelium,ventral blood island,vitelline vein

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Expression summary for pitx2

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Experiment	Species	Images	Stages	Anatomy	Assay
Paper	laevis	1 image	NF stage 31	lateral plate mesoderm	in situ hybridization
Paper	xenopus	1 image	NF stage 33 and 34 to NF stage 35 and 36	lateral plate mesoderm	in situ hybridization
ALK4 functions as a receptor for multiple TGF beta-related ligands to regulate left-right axis determination and mesoderm ind... Paper	laevis	1 image	NF stage 26 to NF stage 28	lateral plate mesoderm	in situ hybridization
Fakhro KA et al. (2011) Assay Paper	tropicalis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos. Paper	laevis	1 image	NF stage 25 to NF stage 26	lateral plate mesoderm	in situ hybridization
The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos. Paper	laevis	1 image	NF stage 25 to NF stage 26	lateral plate mesoderm	in situ hybridization
The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos. Paper	laevis	1 image	NF stage 25 to NF stage 26	lateral plate mesoderm	in situ hybridization
RFX2 is broadly required for ciliogenesis during vertebrate development. Paper	laevis	3 images	NF stage 26	lateral plate mesoderm	in situ hybridization
Cast AE et al. (2012) Assay Paper	laevis	1 image	NF stage 29 and 30	lateral plate mesoderm	in situ hybridization
Myogenic waves and myogenic programs during Xenopus embryonic myogenesis. Paper	laevis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
Serotonin signaling is required for Wnt-dependent GRP specification and leftward flow in Xenopus. Paper	laevis	2 images	NF stage 28 to NF stage 33 and 34	lateral plate mesoderm	in situ hybridization
Symmetry breakage in the frog Xenopus: Role of Rab11 and the ventral-right blastomere. Paper	laevis	1 image	NF stage 29 and 30	dorsal lateral plate mesoderm	in situ hybridization
More than 95% reversal of left-right axis induced by right-sided hypodermic microinjection of activin into Xenopus neurula e... Paper	laevis	1 image	NF stage 24	lateral plate mesoderm	in situ hybridization
Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenes... Paper	laevis	1 image	NF stage 24	lateral plate mesoderm	in situ hybridization
Griffin JN et al. (2015) Assay Paper	tropicalis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
Walentek P et al. (2012) Assay Paper	laevis	1 image	NF stage 35 and 36	lateral plate mesoderm	in situ hybridization
Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia. Paper	tropicalis	1 image	NF stage 28 to NF stage 31	lateral plate mesoderm	in situ hybridization
Left-right lineage analysis of the embryonic Xenopus heart reveals a novel framework linking congenital cardiac defects and ... Paper	laevis	1 image	NF stage 25	lateral plate mesoderm	in situ hybridization
IP3 signaling is required for cilia formation and left-right body axis determination in Xenopus embryos. Paper	laevis	1 image	NF stage 29 and 30	lateral plate mesoderm	in situ hybridization
HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a Nodal- and Lefty ... Paper	laevis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
RAPGEF5 Regulates Nuclear Translocation of β-Catenin. Paper	tropicalis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Paper	laevis	1 image	NF stage 26	lateral plate mesoderm	in situ hybridization
Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways. Paper	laevis	2 images	NF stage 28	lateral plate mesoderm	in situ hybridization
A Conserved Role of the Unconventional Myosin 1d in Laterality Determination. Paper	laevis	3 images	NF stage 24 to NF stage 32	lateral plate mesoderm	in situ hybridization
Tanaka K et al. (2014) Assay Paper	laevis	2 images	NF stage 25	lateral plate mesoderm	in situ hybridization
Kulkarni SS and Khokha MK (2018) Assay Paper	tropicalis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus. Paper	laevis	2 images	NF stage 28 to NF stage 33 and 34	lateral plate mesoderm	in situ hybridization
Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus. Paper	tropicalis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
Griffin JN et al. (2018) Assay Paper	tropicalis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
Nucleoporin NUP205 plays a critical role in cilia and congenital disease. Paper	tropicalis	1 image	NF stage 28	anterior ventral blood island, lateral plate mesoderm	in situ hybridization
Single-minded 2 is required for left-right asymmetric stomach morphogenesis. Paper	laevis	1 image	NF stage 35 and 36 to NF stage 40	smooth muscle	in situ hybridization
Maerker M et al. (2021) Assay Paper	laevis	6 images	NF stage 32	lateral plate mesoderm	in situ hybridization
Sempou E et al. (2022) Assay Paper	tropicalis	1 image	NF stage 28	lateral plate mesoderm	in situ hybridization
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease. Paper	tropicalis	2 images	NF stage 28	lateral plate mesoderm	in situ hybridization
Deniz E et al. (2023) Assay Paper	tropicalis	3 images	NF stage 28 to NF stage 31	lateral plate mesoderm	in situ hybridization
R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient. Paper	laevis	1 image	NF stage 31	lateral plate mesoderm	in situ hybridization

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