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shhxenopus anatomical space 

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Experiment details for shh

Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase.

Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase.

Gene Clone Species Stages Anatomy
shh xenopus NF stage 13 to NF stage 21 archenteron
shh xenopus NF stage 29 and 30 to NF stage 35 and 36 archenteron

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  Fig. 2. Developmental expression profiles of DHCR7 and Shh. (A) RT-PCR analysis of DHCR7 and Shh expression during Xenopus development. H4, histone H4. (B) Whole-mount in situ hybridization of DHCR7 and Shh at gastrula (a,e), neurula (b-d,f-h,i,j,m,n), tadpole (k,l,o,p) stages. (a,b,d,e,f,h) Dorsal views. (c,g) Anterior views. (i-p) Lateral views with anterior towards the left and dorsal upwards. dl, dorsal lip; fp, floor plate; arc, archenteron; tel, telencephalon; ave, anterior ventral endoderm; ba, branchial arches; fnr, frontonasal region; age, presumptive anterior gut endoderm; nd, notochord; ov, otic vesicle. (C) Induction of DHCR7 by activin in animal cap explants. CHX, cycloheximide; WE, whole embryos.