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Gene/CloneSpeciesStageAnatomy ItemExperimenter
agrnxenopus muscle 

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Experiment details for agrn

Former neuritic pathways containing endogenous neural agrin have high synaptogenic activity.

Former neuritic pathways containing endogenous neural agrin have high synaptogenic activity.

Gene Clone Species Stages Anatomy
agrn.L laevis NF stage 40 to NF stage 66 muscle

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  FIG. 1. AChR accumulation at sites of muscle contact with former neuritic pathways containing substrate-bound neural agrin. (A) Muscle cells after 1 day in culture. (B) Agrin immunofluorescence. (C) AChR fluorescence. Similarly numbered arrows in B and C point to the same s i t.es. AChR accumulated at sites where muscle cells contacted the agrin path ways. Arrow heads point to characteristic AChR patches on muscle cells which did not contact agrin pathways. Bar, 25;;m.

Gene Clone Species Stages Anatomy
agrn.L laevis NF stage 40 to NF stage 66 muscle

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  FIG. 2. AChR accumulation confined to the borders of the agrin pathway. (A) Muscle cells after 1 day in culture. (B) Agrin immunofluorescence. (C) AChR fluorescence. Almost all of the AChR accumulation is limited to the width of the agrin pathway. Bar, 5 .um.