| |
Fig. 3. Bicaudal-C is not required for pronephros formation. (A–D) Histological analysis of transverse sections from uninjected and xBic-C-MO1 + 2-injected embryos at stage 45 (A, B) and stage 38 (C, D). Note the edema and the enlarged pronephric tubules in embryos lacking xBic-C. (E, F) Whole mount in situ hybridization of β1-Na/K ATPase of uninjected and xBic-C-MO1 + 2-injected embryos. (G) Fluorescence-labeled Dextran injected into the heart of xBic-C-MO1 + 2-injected Xenopus embryos is excreted via the pronephros. Arrow indicates the cloaca. en, endoderm; no, notochord; nt, neural tube; pn, pronephros; so, somite. |
