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Figure 3. Cyp26a is expressed interdigitally during mid to late limb development. Dark blue stain indicates expression, roman numerals indicate digit identity. A–D:Cyp26a expression in hindlimbs at stages 51 to 55. A:Cyp26a is not expressed at st. 51. B: At st. 53, a diffuse staining can be seen in the distal 2/3 of the limb, with the proximal limit marked by white arrows. C: At st. 54 Cyp26a is expressed between digits IV and III and III and II, marked by black arrowheads. D:Cyp26a is expressed between all five digits at st. 55 (black arrowheads), in two stripes at the base of each forming digit (yellow arrows), and in two stripes in the anterior limb (white arrows). |
