| Search Criteria |
| Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
|---|---|---|---|---|
| fbn2 | xenopus | somite [+] |
Too many results?Too few results?
Experiment details for fbn2
Skoglund P and Keller R (2007) Assay
|
Display additional annotations [+] |
||||||||||
| Fig. 4. Effect of CB-1 peptide on development. (A) CB-1-injected embryos exhibit marked axis shortening and open blastopores. (B) Sibling embryos to those in panel A injected with scrambled peptide develop normally. Scale bars in panels A and B are 1 mm. (C–F) Embryos injected with 300 ng CB-1 peptide exhibiting graded levels of gastrulation arrest that correlates with fibrillin antibody staining. Scale bars for panels C–F is 0.5 mm. (C) An injected embryo exhibiting strong gastrulation arrest exhibits little fibrillin staining and a large open blastopore and will develop into an embryo such as shown in panel A. (D) An embryo that is progressively better at closing its blastopore exhibits progressively more fibrillin staining. The majority of injected embryos appear like those in panel C or D. (E) Embryos that do close their blastopore can exhibit fibrillin staining defects, such as the somitic staining on only one side seen in dorsal view here (side lacking fibrillin staining indicated by arrow). (F) A few injected embryos exhibit normal fibrillin staining but still exhibit a slightly abnormal morphology. (G) Time-lapse sequence showing failure of blastopore closure in an injected embryo; compare to Fig. 1H for normal closure. Scale bar is 0.5 mm. AF = axial fibrillin staining; YP = yolk plug. |