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Fig. 1. Sequence of X. laevis FoxD2. (A) Nucleotide and derived amino acid sequences. The sequence has been deposited under EMBL accession number AJ344435. The TATA box, the polyadenylation signal and the fork head/winged helix domain are underlined. (B) Sequence alignment of X. laevis (x) FoxD2 with chicken (g) FoxD2, X. laevis FoxD1 and FoxD3. Identical aa residues are shown in red, deletions are indicated by dashes. (C) Phylogenetic tree for X. laevis FoxD1 (xBF-2; AJ011652), FoxD2, FoxD3 (XFD-6; AJ298865), human FOXD1 (FREAC4; U59831), chicken FoxD2 (CWH1; U37272) and FoxD3 (CWH3; U37274) (DNAstar program using J. Hein method with PAM 250). (D) Comparative whole mount in situ hybridisation for FoxD1, FoxD2 and FoxD3 during (upper; anterior view) or after completion of neurulation (lower; lateral view), respectively. |
