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Fig. 7. Voltage-dependent potassium (Kv) subunits are differentially
expressed in developing Xenopus retinal ganglion cell (RGC)
growth cones. Stage 24 eye primordia were grown in culture for 24–48
hours and labelled with various Kv subunit antibodies. A: Phase
micrograph of the same RGC axons shown in B. Arrowhead points to
a filopodia. B: The Kv1.3 channel antibody labels the axon abundantly,
but not the body of the growth cone, nor the filopodia or
lamellipodia. C: The Kv1.5 antibody labels the RGC axon and the
entire growth cone, including the filopodia (arrowhead). D: The Kv4.2
antibody labels the RGC axon and growth cone in a punctate manner.
Scale bar 16 m for A–D. |