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kmt2dxenopus eye 

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Experiment details for kmt2d

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis.

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis.

Gene Clone Species Stages Anatomy
kmt2d.L laevis NF stage 28 eye

  kmt2d ( lysine methyltransferase 2D ) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 28, lateral view, anterior left, dorsal up.

Gene Clone Species Stages Anatomy
kmt2d.L laevis NF stage 29 and 30 eye

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  Figure 1: Kmt2d is expressed at early stages of Xenopus development. Kmt2d expression was analyzed by in situ hybridization. A 2-cell stage embryo. B Embryo at blastula stage 8. C Embryo at gastrula stage 10.5. D Embryo at neurula stage 14, anterior view. Arrow marks Kmt2d expression in the anterior region. E Embryo at stage 17, anterior view. F Same embryo as in E, dorsal view. G Embryo at stage 22, lateral view. H Embryo at stage 29 lateral view. I Embryo at neurula stage 14, the dashed line indicates the plane of the sagittal section shown in J. Abbreviations: a (anterior), e (eye), ea (eye anlage), ect (ectoderm), en (endoderm), m (mesoderm), s (somites), p (posterior), pn (premigratory neural crest).