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Search Criteria

Gene/Clone	Species	Stage	Anatomy Item	Experimenter
nkx2-5	xenopus		endoderm [+] hypochord,head endoderm,archenteron,archenteron floor,gastrocoel roof plate,post-anal gut,central endoderm,endodermal cell,vegetal endoderm,suprablastoporal endoderm,sub-blastoporal endoderm,dorsal endoderm,pharyngeal endoderm,hindgut primordium,midgut primordium,foregut endoderm,dorsal crest of the endoderm,monociliated cell,archenteron roof midline,left-right organizer primordium,left-right organizer,ventral endoderm,posterior endoderm,anterior endoderm,Roux spot,acinar cell,alpha cell,anterior foregut,anterior hindgut endoderm,antrum,archenteron floor,archenteron roof midline,beta cell,blastopore lip,capillary system of liver,cardia,colon,delta cell,distal stomach,dorsal endoderm,dorsal foregut,dorsal pancreatic bud,dorsal posterior hindgut endoderm,duodenum,enteric neuron,epsilon cell,exocrine pancreas,external coil of the small intestine,fasciculated network of fibrils,first pancreatic bud,foregut epithelium,fundus,gall bladder,gall bladder primordium,gamma cell,gastrocoel roof plate,germinal vesicle,hepato-pancreatic progenitor cell,hepatocyte,hindgut endoderm,ileum,internal coil of the small intestine,intestinal stem cell,islets of Langerhans,left-right organizer,left-right organizer primordium,liver diverticulum,liver parenchyme,liver primordium,lower blastopore lip,lung bud,lung primordium,mitochondrial cloud,monociliated cell,oocyte cortex,ooplasm,post-anal gut,posterior foregut,posterior hindgut endoderm,proximal stomach,pulmonary epithelium,pyloric sphincter,pylorus,rectum,ring structure,second pancreatic bud,stomach,stomach body,stomach epithelium,subcortical cytoplasm,tracheoesophageal fold,tracheoesophageal septum,transient tracheoesophageal septum,upper blastopore lip,vegetal cortex,ventral foregut,ventral posterior hindgut endoderm,wedge region,yolk platelet,anterior endoderm,anterior hindgut endoderm,archenteron,bile duct,biliary tree,blastopore,buccopharyngeal membrane,central endoderm,cloacal sphincter,dorsal endoderm,dorsal pancreatic bud,dorsal posterior hindgut endoderm,egg,first pancreatic bud,foregut,foregut endoderm,foregut epithelium,gall bladder,gall bladder primordium,head endoderm,hepato-pancreatic duct,hepato-pancreatic progenitor cell,hindgut,hindgut endoderm,hindgut primordium,hypochord,islets of Langerhans,large intestine,left-right organizer,liver,liver diverticulum,liver parenchyme,liver primordium,lung,lung bud,lung primordium,midgut,midgut primordium,oocyte,oral evagination,pancreas,pharyngeal cavity,pharyngeal endoderm,pharyngeal pouch,polar body,posterior endoderm,posterior hindgut endoderm,primary oogonium,primary spermatogonium,primordial germ cell,proctodeum,pyloric sphincter,second pancreatic bud,secondary oogonium,secondary spermatogonium,small intestine,spermatid,spermatocyte,spermatozoon,stomach,stomach epithelium,sub-blastoporal endoderm,suprablastoporal endoderm,taste bud,thyroid,thyroid primordium,urostyle,ventral endoderm,ventral pancreatic bud,ventral posterior hindgut endoderm,visceral pouch

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Expression summary for nkx2-5

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Experiment	Species	Images	Stages	Anatomy	Assay
Ondine B. Cleaver	laevis	1 image	NF stage 29 and 30	endoderm, foregut	in situ hybridization
Zorn Lab Assay Zorn Lab	laevis	1 image	NF stage 19	endoderm, foregut	in situ hybridization
Zorn Lab Assay Zorn Lab	laevis	1 image	NF stage 22	endoderm, foregut	in situ hybridization
Zorn Lab Assay Zorn Lab	laevis	1 image	NF stage 33 and 34	endoderm, foregut, visceral pouch	in situ hybridization
Peterkin T et al. (2007) Assay Paper	laevis	1 image	NF stage 16 to NF stage 17	endoderm	in situ hybridization
Parlier D et al. (2009) Assay Paper	laevis	1 image	NF stage 22	endoderm, foregut	in situ hybridization
Zorn Xl.22859_nkx2-5 Assay Zorn Lab	laevis	3 images	NF stage 13 to NF stage 35 and 36	endoderm, foregut	in situ hybridization
Keren-Politansky A et al. (2009) Assay Paper	laevis	1 image	NF stage 13	endoderm	in situ hybridization
Cardiac specific expression of Xenopus Popeye-1. Paper	laevis	1 image	NF stage 33 and 34 to NF stage 35 and 36	visceral pouch	in situ hybridization
Regulation of the tinman homologues in Xenopus embryos. Paper	laevis	1 image	NF stage 22 to NF stage 40	endoderm, foregut	in situ hybridization
Regulation of the tinman homologues in Xenopus embryos. Paper	laevis	1 image	NF stage 26 to NF stage 32	endoderm	in situ hybridization
Regulation of the tinman homologues in Xenopus embryos. Paper	laevis	1 image	NF stage 22 to NF stage 32	endoderm, foregut	in situ hybridization
Subdivision of the cardiac Nkx2.5 expression domain into myogenic and nonmyogenic compartments. Paper	xenopus	1 image	NF stage 22 to NF stage 28	endoderm, foregut	in situ hybridization
A role for GATA-4/5/6 in the regulation of Nkx2.5 expression with implications for patterning of the precardiac field. Paper	xenopus	1 image	NF stage 35 and 36	endoderm	in situ hybridization
Clone: Xnkx2.5 derived probe in situ hybridization	laevis	1 image	NF stage 29 and 30	foregut	in situ hybridization
Retinoic acid can block differentiation of the myocardium after heart specification. Paper	laevis	1 image	NF stage 32	visceral pouch	in situ hybridization
Early cardiac morphogenesis defects caused by loss of embryonic macrophage function in Xenopus. Paper	laevis	1 image	NF stage 25	endoderm	in situ hybridization
Li Y et al. (2008) Assay Paper	laevis	1 image	NF stage 20	endoderm, foregut	in situ hybridization
A role for the RNA-binding protein, hermes, in the regulation of heart development. Paper	laevis	1 image	NF stage 28 to NF stage 29 and 30	endoderm, foregut	in situ hybridization
Xenbase User Curated Experiment	laevis	1 image	NF stage 33 and 34	foregut	in situ hybridization
Xenbase User Curated Experiment	laevis	1 image	NF stage 33 and 34	foregut	in situ hybridization
Xenbase User Curated Experiment	laevis	1 image	NF stage 26	foregut	in situ hybridization
Embryonic origins of spleen asymmetry. Paper	laevis	1 image	NF stage 43	pancreas	in situ hybridization
XNkx-2.5, a Xenopus gene related to Nkx-2.5 and tinman: evidence for a conserved role in cardiac development. Paper	laevis	1 image	NF stage 18 to NF stage 40	archenteron, foregut, visceral pouch	in situ hybridization
Small EM et al. (2005) Assay Paper	laevis	1 image	NF stage 29 and 30 to NF stage 33 and 34	endoderm	in situ hybridization
A crucial role of a high mobility group protein HMGA2 in cardiogenesis. Paper	laevis	1 image	NF stage 33 and 34	visceral pouch	in situ hybridization
A crucial role of a high mobility group protein HMGA2 in cardiogenesis. Paper	laevis	1 image	NF stage 33 and 34	visceral pouch	in situ hybridization
Acosta H et al. (2015) Assay Paper	laevis	2 images	NF stage 18 to NF stage 20	endoderm, foregut, foregut endoderm	in situ hybridization
Zhu W et al. (2008) Assay Paper	laevis	1 image	NF stage 37 and 38 to NF stage 42	foregut	in situ hybridization
A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification.	laevis	1 image	NF stage 33 and 34	endoderm, foregut, lung primordium	immunohistochemistry
Prolonged FGF signaling is necessary for lung and liver induction in Xenopus. Paper	laevis	1 image	NF stage 35 and 36	liver primordium, ventral foregut	in situ hybridization
Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs. Paper	laevis	1 image	NF stage 20	foregut	in situ hybridization
Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs. Paper	laevis	1 image	NF stage 35 and 36	foregut	in situ hybridization

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