|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
tbx1
|
|
laevis
|
NF stage 15
to
NF stage 20
|
lateral plate mesoderm
,
anterior
,
cardiac progenitor cell
|
tbx1
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
heart
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
branchial arch
,
[+]
|
fgf8
|
|
laevis
|
NF stage 15
to
NF stage 29 and 30
|
midbrain-hindbrain boundary
,
neuroectoderm
,
mesoderm
,
pharyngeal arch
,
mandibular arch
,
[+]
|
isl1
|
|
laevis
|
NF stage 15
to
NF stage 20
|
lateral plate mesoderm
,
cardiac progenitor cell
|
isl1
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
heart
,
heart primordium
,
anterior
|
dkk1
|
|
laevis
|
NF stage 15
to
NF stage 20
|
eye primordium
,
cranial placode
,
anterior neural tube
,
cardiac progenitor cell
|
dkk1
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
forebrain
,
heart
,
cardiac mesoderm
,
heart primordium
|
bmp2
|
|
laevis
|
NF stage 15
to
NF stage 20
|
lateral plate mesoderm
,
cardiac progenitor cell
|
bmp4
|
|
laevis
|
NF stage 15
to
NF stage 20
|
neural groove
,
neural plate
,
lateral plate mesoderm
,
cardiac progenitor cell
|
gata5
|
|
laevis
|
NF stage 15
to
NF stage 20
|
mesoderm
,
cardiac progenitor cell
|
gata5
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
cardiac mesoderm
,
ventral
,
heart primordium
|
gata6
|
|
laevis
|
NF stage 15
to
NF stage 20
|
lateral plate mesoderm
,
cardiac progenitor cell
|
gata6
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
alimentary system
,
intestine
,
liver and biliary system
,
cardiac mesoderm
,
heart primordium
,
[+]
|
tbx5
|
|
laevis
|
NF stage 15
to
NF stage 20
|
neural plate
,
lateral plate mesoderm
,
cardiac progenitor cell
|
tbx5
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
heart
,
cardiac mesoderm
,
heart primordium
|
tbx20
|
|
laevis
|
NF stage 15
|
cardiac progenitor cell
|
tbx20
|
|
laevis
|
NF stage 20
|
cement gland primordium
,
cardiac progenitor cell
|
tbx20
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
heart primordium
,
cardiac progenitor cell
|
gata4
|
|
laevis
|
NF stage 15
to
NF stage 20
|
cardiac progenitor cell
|
gata4
|
|
laevis
|
NF stage 20
to
NF stage 29 and 30
|
cardiac mesoderm
,
lateral plate mesoderm
,
heart primordium
,
cardiac progenitor cell
|
nkx2-5
|
|
laevis
|
NF stage 15
to
NF stage 20
|
lateral plate mesoderm
,
cardiac progenitor cell
|
kdr
|
|
laevis
|
NF stage 15
to
NF stage 20
|
cardiac progenitor cell
|
kdr
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
heart primordium
,
vascular endothelium
,
cardiac progenitor cell
|
aplnr
|
|
laevis
|
NF stage 15
to
NF stage 20
|
lateral plate mesoderm
,
cardiac progenitor cell
|
aplnr
|
|
laevis
|
NF stage 24
to
NF stage 29 and 30
|
heart primordium
,
vascular endothelium
,
cardiac progenitor cell
|
|
|
Fig. 2. (A) Cardiac expression of Isl1, Nkx2.5, GATA4, GATA5, GATA6b, Xmsr and Flk1 in Xenopus embryos at stages 15/16, 20, 24 and 29 as indicated. (B) Cardiac expression of Tbx20, Tbx1, Tbx5, BMP2, BMP4, Dkk1, and FGF8b at different developmental stages of Xenopus laevis as indicated. For embryos at stages 15/16 and 20 anterior views are presented, whereas embryos at stage 24 and 29 are shown from the ventral side, anterior is to the top. Dotted lines indicate the cement gland. |