| Search Criteria |
| Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
|---|---|---|---|---|
| rapgef5 | xenopus | blastomere [+] |
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Experiment details for rapgef5
RAPGEF5 Regulates Nuclear Translocation of β-Catenin.RAPGEF5 Regulates Nuclear Translocation of β-Catenin.
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| Figure S5. Related to Fig. 6; Developmental expression of Rapgef5 and Rap genes. In situ hybridization reveals rapgef5 mRNA is present from the earliest stages of development. It is detected in the animal pole at the 2 cell and 8 cell stages. In the stage 10 embryos expression appears diffuse around the blastopore. At stage 14 transcripts are detected in the anterior neural folds and forming GRP. rapgef5 expression is restricted to the anterior neural tube, brain, pharyngeal arches and cranial placodes at stage 28. rap1A, rap2A and rap2B are all expressed in the 4 cell embryo, in the gastrulating stage 10 embryo and in the GRP at stage 16. Expression of all three genes is also strong in the neural folds at stage 16, while rap2B also displays a speckled pattern on the lateral ectoderm. All three are expressed in the neural tube, brain, eye and pharyngeal arches at stage 28. | ||||||||||||||||
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| rapgef5 (Rap guanine nucleotide exchange factor 5) gene expression in Xenopus tropicalis embryo, assayed via in situ hybridization, NF stage 2, horizontal view, animal up. |