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Search Criteria

Gene/Clone	Species	Stage	Anatomy Item	Experimenter
shh	xenopus		endoderm [+] hypochord,head endoderm,archenteron,archenteron floor,gastrocoel roof plate,post-anal gut,central endoderm,endodermal cell,vegetal endoderm,suprablastoporal endoderm,sub-blastoporal endoderm,dorsal endoderm,pharyngeal endoderm,hindgut primordium,midgut primordium,foregut endoderm,dorsal crest of the endoderm,monociliated cell,archenteron roof midline,left-right organizer primordium,left-right organizer,ventral endoderm,posterior endoderm,anterior endoderm,Roux spot,acinar cell,alpha cell,anterior foregut,anterior hindgut endoderm,antrum,archenteron floor,archenteron roof midline,beta cell,blastopore lip,capillary system of liver,cardia,colon,delta cell,distal stomach,dorsal endoderm,dorsal foregut,dorsal pancreatic bud,dorsal posterior hindgut endoderm,duodenum,enteric neuron,epsilon cell,exocrine pancreas,external coil of the small intestine,fasciculated network of fibrils,first pancreatic bud,foregut epithelium,fundus,gall bladder,gall bladder primordium,gamma cell,gastrocoel roof plate,germinal vesicle,hepato-pancreatic progenitor cell,hepatocyte,hindgut endoderm,ileum,internal coil of the small intestine,intestinal stem cell,islets of Langerhans,left-right organizer,left-right organizer primordium,liver diverticulum,liver parenchyme,liver primordium,lower blastopore lip,lung bud,lung primordium,mitochondrial cloud,monociliated cell,oocyte cortex,ooplasm,post-anal gut,posterior foregut,posterior hindgut endoderm,proximal stomach,pulmonary epithelium,pyloric sphincter,pylorus,rectum,ring structure,second pancreatic bud,stomach,stomach body,stomach epithelium,subcortical cytoplasm,tracheoesophageal fold,tracheoesophageal septum,transient tracheoesophageal septum,upper blastopore lip,vegetal cortex,ventral foregut,ventral posterior hindgut endoderm,wedge region,yolk platelet,anterior endoderm,anterior hindgut endoderm,archenteron,bile duct,biliary tree,blastopore,buccopharyngeal membrane,central endoderm,cloacal sphincter,dorsal endoderm,dorsal pancreatic bud,dorsal posterior hindgut endoderm,egg,first pancreatic bud,foregut,foregut endoderm,foregut epithelium,gall bladder,gall bladder primordium,head endoderm,hepato-pancreatic duct,hepato-pancreatic progenitor cell,hindgut,hindgut endoderm,hindgut primordium,hypochord,islets of Langerhans,large intestine,left-right organizer,liver,liver diverticulum,liver parenchyme,liver primordium,lung,lung bud,lung primordium,midgut,midgut primordium,oocyte,oral evagination,pancreas,pharyngeal cavity,pharyngeal endoderm,pharyngeal pouch,polar body,posterior endoderm,posterior hindgut endoderm,primary oogonium,primary spermatogonium,primordial germ cell,proctodeum,pyloric sphincter,second pancreatic bud,secondary oogonium,secondary spermatogonium,small intestine,spermatid,spermatocyte,spermatozoon,stomach,stomach epithelium,sub-blastoporal endoderm,suprablastoporal endoderm,taste bud,thyroid,thyroid primordium,urostyle,ventral endoderm,ventral pancreatic bud,ventral posterior hindgut endoderm,visceral pouch

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Expression summary for shh

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Experiment	Species	Images	Stages	Anatomy	Assay
López SL et al. (2003) Assay Paper	laevis	1 image	NF stage 10.25 to NF stage 13	blastopore, blastopore lip, upper blastopore lip	in situ hybridization
Lupo G et al. (2005) Assay Paper	xenopus	1 image	NF stage 33 and 34	liver diverticulum	in situ hybridization
The presumptive floor plate (notoplate) induces behaviors associated with convergent extension in medial but not lateral neur... Paper	laevis	1 image	NF stage 11 to NF stage 13	blastopore lip	in situ hybridization
Cholesterol homeostasis in development: the role of Xenopus 7-dehydrocholesterol reductase (Xdhcr7) in neural development. Paper	laevis	1 image	NF stage 33 and 34	hypochord	in situ hybridization
Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Paper	xenopus	1 image	NF stage 10 to NF stage 35 and 36	archenteron, endoderm, liver diverticulum, upper blastopore lip	in situ hybridization
Olfactory and lens placode formation is controlled by the hedgehog-interacting protein (Xhip) in Xenopus. Paper	laevis	1 image	NF stage 32	liver primordium, visceral pouch	in situ hybridization
Xenbase User Curated Experiment European Xenopus Resource Centre (EXRC)	tropicalis	1 image	NF stage 32	foregut, gall bladder primordium	in situ hybridization
Xenbase User Curated Experiment European Xenopus Resource Centre (EXRC)	tropicalis	1 image	NF stage 11	blastopore lip, upper blastopore lip	in situ hybridization
Expression of components of Wnt and Hedgehog pathways in different tissue layers during lung development in Xenopus laevis. Paper	laevis	1 image	NF stage 41	lung	in situ hybridization
Takabatake T et al. (2000) Assay Paper	laevis	2 images	NF stage 27 to NF stage 35 and 36	endoderm, foregut, gall bladder primordium	in situ hybridization
Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis. Paper	laevis	1 image	NF stage 29 and 30	liver diverticulum	in situ hybridization
Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional scre... Paper	tropicalis	1 image	NF stage 13	upper blastopore lip	in situ hybridization
Rankin SA et al. (2012) Assay Paper	laevis	2 images	NF stage 33 and 34 to NF stage 35 and 36	endoderm, foregut, gall bladder primordium	in situ hybridization
Beck CW and Slack JM (1998) Assay Paper	laevis	1 image	NF stage 32	hypochord	in situ hybridization
Sulf1 influences the Shh morphogen gradient during the dorsal ventral patterning of the neural tube in Xenopus tropicalis. Paper	tropicalis	1 image	NF stage 35 and 36	dorsal pancreatic bud, foregut, ventral pancreatic bud	in situ hybridization
Rankin SA et al. (2014) Assay Paper	laevis	1 image	NF stage 32 to NF stage 59	endoderm, foregut, liver diverticulum, liver primordium, lung, [+] lung primordium, stomach	in situ hybridization
The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with t... Paper	laevis	1 image	NF stage 15	hypochord	in situ hybridization
Patient Lab	laevis	11 images	NF stage 10.5 to NF stage 40	endoderm, foregut, gall bladder, gall bladder primordium, proctodeum	in situ hybridization
Koide T et al. (2006) Assay Paper	laevis	1 image	NF stage 22 to NF stage 44	foregut endoderm	in situ hybridization
Peyrot SM et al. (2011) Assay Paper	laevis	3 images	NF stage 10.5 to NF stage 35 and 36	hypochord, upper blastopore lip	in situ hybridization
TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: a new link in the FGF/BMP regulatory network. Paper	laevis	1 image	NF stage 10 to NF stage 10.25	upper blastopore lip	in situ hybridization
A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. Paper	laevis	2 images	NF stage 23 to NF stage 35 and 36	endoderm, foregut, gall bladder primordium, lung primordium	in situ hybridization
Pitcairn E et al. (2017) Assay Paper	laevis	1 image	NF stage 10.5	upper blastopore lip	in situ hybridization
Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. Paper	laevis	2 images	NF stage 35 and 36	endoderm, foregut, foregut endoderm, gall bladder primordium	in situ hybridization

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