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Search Criteria

Gene/Clone	Species	Stage	Anatomy Item	Experimenter
shh	xenopus		endomesoderm [+] dorsal endomesoderm,ventral endomesoderm,anterior endomesoderm,posterior endomesoderm,Eberth-Kastschenko layer,Roux spot,abdominal myoblast,acinar cell,alpha cell,anterior dorsal lateral plate region,anterior endoderm,anterior foregut,anterior hindgut endoderm,anterior notochord,anterior palatine artery,anterior ventral blood island,antrum,archenteron,archenteron floor,archenteron roof midline,atrial septum,atrioventricular canal,atrioventricular canal endocardium,atrioventricular valve,atrioventricular valve leaflet,axial ossicle,beta cell,blastopore lip,capillary system of liver,cardia,cardiac atrium,cardiac jelly,cardiac myocyte,cardiac progenitor cell,cardiac valve,cardiac ventricle,caudal presomitic mesoderm,central endoderm,cerebral artery,chordoneural hinge,cloaca,cloacal sphincter,colon,cranial skeleton,delta cell,dermatome,dermomyotome,distal stomach,distal tubule,dorsal crest of the endoderm,dorsal endoderm,dorsal fin vasculature,dorsal foregut,dorsal lateral plate mesoderm,dorsal pancreatic bud,dorsal posterior hindgut endoderm,dorsomedial edge of myotome,duodenum,early distal tubule,early proximal tubule,endocardial cushion,endocardial tube,endocardium,endodermal cell,endothelial cell,enteric neuron,epicardial precursor cell,epicardium,epsilon cell,exocrine pancreas,external carotid artery,external coil of the small intestine,fasciculated network of fibrils,filter chamber,first pancreatic bud,flexural organ,foregut endoderm,foregut epithelium,fundus,gall bladder,gall bladder primordium,gamete,gamma cell,gastrocoel roof plate,germinal vesicle,glomeral nexus,glomerular epithelial cell,glomerular mesangial cell,glomerulus,glomus,head endoderm,head mesoderm,hematopoietic stem cell,hepato-pancreatic progenitor cell,hepatocyte,hindgut endoderm,hindgut primordium,hypochord,ileum,intermediate mesoderm,internal coil of the small intestine,intestinal stem cell,involuted dorsal mesoderm,involuted ventral mesoderm,islets of Langerhans,late distal tubule,late proximal tubule,lateral plate mesoderm,left atrium,left-right organizer,left-right organizer primordium,liver diverticulum,liver parenchyme,liver primordium,lower blastopore lip,lung bud,lung primordium,mandibular mesenchyme,mesodermal cell,mesonephric collecting duct,mesonephric tubule,midgut primordium,migrating macrophage,mitochondrial cloud,monociliated cell,myocardium,myocoelic slit,myotome,neurenteric canal,notochordal sheath,oocyte cortex,ooplasm,ophthalmic artery,outflow tract,paraxial mesoderm,pericardial muscle,pericardial roof,pericardium,perichordal tissue,pharyngeal endoderm,podocyte,post-anal gut,postcranial axial skeleton,posterior endoderm,posterior foregut,posterior hindgut endoderm,posterior notochord,posterior palatine artery,posterior ventral blood island,posterior wall of neurenteric canal,prechordal plate,presomitic mesoderm,presumptive paraxial mesoderm,pronephric duct,pronephric nephron,pronephric nephrostome,pronephric sinus,pronephric tubule,proximal stomach,proximal tubule,proximal tubule branch,pulmonary epithelium,pyloric sphincter,pylorus,rectal diverticulum,rectum,rib,right atrium,ring structure,rostral presomitic mesoderm,sclerotomal cartilage,sclerotomal mesenchyme,sclerotome,second pancreatic bud,sinus venosus,smooth muscle myocyte,somatic layer of lateral plate mesoderm,somite,spiral septum,splanchnic layer of lateral plate mesoderm,stomach,stomach body,stomach epithelium,stratum compactum,stratum spongiosum,sub-blastoporal endoderm,subcortical cytoplasm,suprablastoporal endoderm,syndetome,trabecula carnea,tracheoesophageal fold,tracheoesophageal septum,transient tracheoesophageal septum,transverse process,upper blastopore lip,urostyle,vacuolated notochordal tissue,vegetal cortex,vegetal endoderm,ventral blood island border,ventral endoderm,ventral fin vasculature,ventral foregut,ventral mesoderm,ventral posterior hindgut endoderm,ventricular outflow tract,ventrolateral edge of myotome,vertebra,vertebral centrum,vertebral column,vertebral element,wedge region,yolk platelet,Mullerian duct,anterior cardinal vein,anterior endoderm,anterior endomesoderm,anterior hindgut endoderm,anterior lymph sac,anterior palatine artery,aortic arch,archenteron,arteria iliaca communis,arteria mesenterica posterior,arteria subclavia,arterial endothelium,axial mesoderm,axial skeleton,bile duct,biliary tree,blastopore,buccopharyngeal membrane,capillary system of liver,cardiac atrium,cardiac mesoderm,cardinal vein,caudal artery,caudal vein,central endoderm,ceratobranchial I,ceratobranchial II,ceratobranchial III,ceratobranchial IV,cerebral artery,cervical vertebra,chondroblast,chondrocyte,circumblastoporal collar,cloacal sphincter,coeliaco-mesenteric artery,coelomic epithelium,commisura quadratocranialis anterior,cornua trabecula,cranial muscle,cranial muscle primordium,dermatome,dermis,dorsal aorta,dorsal endoderm,dorsal endomesoderm,dorsal fin vasculature,dorsal lymph space,dorsal pancreatic bud,dorsal posterior hindgut endoderm,duct of Cuvier,egg,elastica externa,endocardial tube,endocardium,endoderm,epicardium,erythroid cell,external carotid artery,external gill,external jugular vein,facies hyoidis of the palatoquadrate,fin vasculature,first pancreatic bud,flexural organ,foregut,foregut endoderm,foregut epithelium,gall bladder,gall bladder primordium,gastric vein,genital ridge,genital system,gill primordium,glomeral mesenchyme,glomeral nexus,glomus,head endoderm,head mesoderm,head somite 1,head somite 2,head somite 3,head somite 4,heart,heart primordium,hepatic portal vein,hepatic vein,hepato-pancreatic duct,hepato-pancreatic progenitor cell,hindgut,hindgut endoderm,hindgut primordium,hypochord,infrarostral,intermediate mesoderm,internal carotid artery,internal jugular vein,interrenal vein,intersomitic artery,intersomitic vein,intersomitic vessel,islets of Langerhans,kidney,large intestine,larval aorta,lateral plate mesoderm,lateral postcardinal vein,left channel of ventral aorta,left lymph heart,left spleen primordium,liver,liver diverticulum,liver parenchyme,liver primordium,lower blastopore lip,lung,lung bud,lung primordium,lymph vessel,m. cucullaris,m. depressor mandibulae,m. levator scapulae inferior,m. levator scapulae superior,m. petrohyoideus,medial abdominal vein,medial cardinal vein,mesenchymal stem cell,mesoderm,mesonephric duct,mesonephric early distal tubule,mesonephric early proximal tubule,mesonephric late distal tubule,mesonephric late proximal tubule,mesonephric mesenchyme,mesonephric nephron,mesonephric sinus,midgut,midgut primordium,musculoabdominal vein,myeloid cell,myocardium,myotome of head somite 1,myotome of head somite 2,myotome of head somite 3,myotome of head somite 4,myotome of tail somite 14,myotome of tail somite 15,myotome of tail somite 16,myotome of tail somite 17,myotome of tail somite 18,myotome of trunk somite 1,myotome of trunk somite 10,myotome of trunk somite 11,myotome of trunk somite 12,myotome of trunk somite 13,myotome of trunk somite 2,myotome of trunk somite 3,myotome of trunk somite 4,myotome of trunk somite 5,myotome of trunk somite 6,myotome of trunk somite 7,myotome of trunk somite 8,myotome of trunk somite 9,neurenteric canal,notochord,notochordal epithelium,occipitovertebral artery,omphalomesenteric vein,oocyte,oral evagination,oviduct,paired dorsal aorta,palatoquadrati,pancreas,parachordal,paraxial mesoderm,pharyngeal cavity,pharyngeal endoderm,pharyngeal pouch,planum hypobranchiale,planum trabeculare anticum,polar body,posterior cardinal vein,posterior endoderm,posterior endomesoderm,posterior hindgut endoderm,posterior vena cava,posterior ventral blood island,prechordal plate,presomitic mesoderm,presumptive paraxial mesoderm,primary heart field,primary oogonium,primary spermatogonium,primordial germ cell,processus anterior hyalis,processus articularis palatoquadrati,processus ascendens palatoquadrate,processus lateralis hyalis,processus muscularis palatoquadrati,processus posterior hyalis,processus retroarticularis of Meckel's cartilage,proctodeum,proepicardium,pronephric duct,pronephric kidney,pronephric mesenchyme,pronephric nephrostome,pronephric sinus,pulmonary vein,pyloric sphincter,right channel of ventral aorta,right lymph heart,right spleen primordium,sacral vertebra,sclerotome of head somite 4,sclerotome of tail somite 14,sclerotome of tail somite 15,sclerotome of tail somite 16,sclerotome of tail somite 17,sclerotome of tail somite 18,sclerotome of trunk somite 1,sclerotome of trunk somite 10,sclerotome of trunk somite 11,sclerotome of trunk somite 12,sclerotome of trunk somite 13,sclerotome of trunk somite 2,sclerotome of trunk somite 3,sclerotome of trunk somite 4,sclerotome of trunk somite 5,sclerotome of trunk somite 6,sclerotome of trunk somite 7,sclerotome of trunk somite 8,sclerotome of trunk somite 9,second pancreatic bud,secondary heart field,secondary oogonium,secondary spermatogonium,small intestine,smooth muscle,somatic layer of lateral plate mesoderm,somite,spermatid,spermatocyte,spermatozoon,spiral septum,splanchnic layer of lateral plate mesoderm,spleen,stomach,stomach epithelium,sub-blastoporal endoderm,subinterstitial vein,subocular cartilage,suprablastoporal endoderm,suprarostral plate,tail bud,tail somite 14,tail somite 15,tail somite 16,tail somite 17,tail somite 18,tail vein,taste bud,thyroid,thyroid primordium,trabecula carnea,trabecula cranii,trunk somite 1,trunk somite 10,trunk somite 11,trunk somite 12,trunk somite 13,trunk somite 2,trunk somite 3,trunk somite 4,trunk somite 5,trunk somite 6,trunk somite 7,trunk somite 8,trunk somite 9,urostyle,vascular endothelium,venous endothelium,ventral aorta,ventral blood island,ventral blood island border,ventral endoderm,ventral endomesoderm,ventral fin vasculature,ventral pancreatic bud,ventral posterior hindgut endoderm,visceral pouch

Too many results?Too few results?

Expression summary for shh

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Experiment	Species	Images	Stages	Anatomy	Assay
Harland lab in situ screen Assay Harland Lab	tropicalis	1 image	NF stage 20	axial mesoderm, notochord	in situ hybridization
Khokha MK et al. (2005) Assay Paper	tropicalis	2 images	NF stage 14 to NF stage 15	notochord	in situ hybridization
López SL et al. (2003) Assay Paper	xenopus	1 image	NF stage 10.25 to NF stage 15	notochord	in situ hybridization
López SL et al. (2003) Assay Paper	laevis	2 images	NF stage 10.25 to NF stage 15	axial mesoderm, blastopore, blastopore lip, mesoderm, notochord, [+] upper blastopore lip	in situ hybridization
Offner N et al. (2005) Assay Paper	xenopus	1 image	NF stage 15 to NF stage 18	notochord	in situ hybridization
Offner N et al. (2005) Assay Paper	laevis	1 image	NF stage 15 to NF stage 18	prechordal plate	in situ hybridization
Lupo G et al. (2005) Assay Paper	xenopus	2 images	neurula stage to NF stage 33 and 34	liver diverticulum, notochord	in situ hybridization
Silva AC et al. (2003) Assay Paper	laevis	1 image	NF stage 22 to NF stage 24	notochord	in situ hybridization
Howell M et al. (2002) Assay Paper	xenopus	1 image	NF stage 35 and 36	notochord	in situ hybridization
Inomata H et al. (2008) Assay Paper	laevis	2 images	NF stage 13	axial mesoderm	in situ hybridization
Paper	laevis	1 image	NF stage 28	notochord	in situ hybridization
The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo. Paper	laevis	1 image	NF stage 14	axial mesoderm	in situ hybridization
The presumptive floor plate (notoplate) induces behaviors associated with convergent extension in medial but not lateral neur... Paper	laevis	1 image	NF stage 11 to NF stage 13	blastopore lip, notochord	in situ hybridization
Cholesterol homeostasis in development: the role of Xenopus 7-dehydrocholesterol reductase (Xdhcr7) in neural development. Paper	laevis	1 image	NF stage 14 to NF stage 33 and 34	hypochord, notochord, prechordal plate	in situ hybridization
Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Paper	xenopus	1 image	NF stage 10 to NF stage 35 and 36	archenteron, endoderm, liver diverticulum, notochord, upper blastopore lip	in situ hybridization
Olfactory and lens placode formation is controlled by the hedgehog-interacting protein (Xhip) in Xenopus. Paper	laevis	1 image	NF stage 32	liver primordium, mesoderm, notochord, visceral pouch	in situ hybridization
Neural tube closure requires Dishevelled-dependent convergent extension of the midline. Paper	laevis	1 image	NF stage 21	axial mesoderm	in situ hybridization
Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development. Paper	laevis	1 image	NF stage 26 to NF stage 31	notochord, prechordal plate	in situ hybridization
Neuroectodermal specification and regionalization of the Spemann organizer in Xenopus. Paper	xenopus	1 image	NF stage 10 to NF stage 12.5	notochord	in situ hybridization
Xenbase User Curated Experiment European Xenopus Resource Centre (EXRC)	tropicalis	1 image	NF stage 32	foregut, gall bladder primordium, notochord	in situ hybridization
Xenbase User Curated Experiment European Xenopus Resource Centre (EXRC)	tropicalis	1 image	NF stage 11	blastopore lip, mesoderm, upper blastopore lip	in situ hybridization
Expression of components of Wnt and Hedgehog pathways in different tissue layers during lung development in Xenopus laevis. Paper	laevis	1 image	NF stage 41	lung	in situ hybridization
Xenopus sonic hedgehog guides retinal axons along the optic tract. Paper	laevis	1 image	NF stage 32 to NF stage 37 and 38	notochord	in situ hybridization
The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning. Paper	laevis	1 image	NF stage 13	axial mesoderm, notochord	in situ hybridization
The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis. Paper	laevis	1 image	NF stage 13 to NF stage 14	notochord	in situ hybridization
Takabatake T et al. (2000) Assay Paper	laevis	2 images	NF stage 27 to NF stage 35 and 36	axial mesoderm, endoderm, foregut, gall bladder primordium, notochord	in situ hybridization
Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis. Paper	laevis	1 image	NF stage 29 and 30	chordoneural hinge, liver diverticulum	in situ hybridization
Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional scre... Paper	tropicalis	1 image	NF stage 13 to NF stage 28	axial mesoderm, involuted dorsal mesoderm, notochord, prechordal plate, upper blastopore lip	in situ hybridization
Rankin SA et al. (2012) Assay Paper	laevis	2 images	NF stage 33 and 34 to NF stage 35 and 36	endoderm, foregut, gall bladder primordium, notochord	in situ hybridization
Beck CW and Slack JM (1998) Assay Paper	laevis	1 image	NF stage 32	chordoneural hinge, hypochord, notochord, tail bud	in situ hybridization
Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis. Paper	laevis	1 image	NF stage 14 to NF stage 29 and 30	axial mesoderm, notochord	in situ hybridization
Multiple stage-dependent roles for histone deacetylases during amphibian embryogenesis: implications for the involvement of ... Paper	laevis	1 image	NF stage 33 and 34 to NF stage 35 and 36	notochord	in situ hybridization
Scaling of dorsal-ventral patterning by embryo size-dependent degradation of Spemann''s organizer signals. Paper	laevis	1 image	NF stage 12.5	notochord	in situ hybridization
Scaling of dorsal-ventral patterning by embryo size-dependent degradation of Spemann''s organizer signals. Paper	laevis	1 image	NF stage 13	notochord	in situ hybridization
Sulf1 influences the Shh morphogen gradient during the dorsal ventral patterning of the neural tube in Xenopus tropicalis. Paper	tropicalis	1 image	NF stage 15 to NF stage 35 and 36	notochord	immunohistochemistry
Sulf1 influences the Shh morphogen gradient during the dorsal ventral patterning of the neural tube in Xenopus tropicalis. Paper	tropicalis	1 image	NF stage 15 to NF stage 35 and 36	anterior ventral blood island, dorsal pancreatic bud, foregut, notochord, tail bud, [+] ventral pancreatic bud	in situ hybridization
Rankin SA et al. (2014) Assay Paper	laevis	1 image	NF stage 32 to NF stage 59	endoderm, foregut, liver diverticulum, liver primordium, lung, [+] lung primordium, notochord, stomach	in situ hybridization
The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with t... Paper	laevis	1 image	NF stage 15 to NF stage 27	hypochord, notochord	in situ hybridization
Stolow MA and Shi YB (1995) Assay Paper	laevis	1 image	NF stage 32	notochord	in situ hybridization
E2a is necessary for Smad2/3-dependent transcription and the direct repression of lefty during gastrulation. Paper	laevis	1 image	NF stage 29 and 30	notochord	in situ hybridization
Patient Lab	laevis	25 images	NF stage 10.5 to NF stage 40	axial mesoderm, endoderm, foregut, gall bladder, gall bladder primordium, [+] mesoderm, notochord, proctodeum, ventral blood island	in situ hybridization
Koide T et al. (2006) Assay Paper	laevis	2 images	NF stage 22 to NF stage 44	foregut endoderm, notochord	in situ hybridization
Branford WW and Yost HJ (2002) Assay Paper	laevis	1 image	NF stage 26 to NF stage 27	axial mesoderm, notochord	in situ hybridization
Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos. Paper	laevis	1 image	NF stage 24	notochord	in situ hybridization
Peyrot SM et al. (2011) Assay Paper	laevis	5 images	NF stage 10.5 to NF stage 35 and 36	hypochord, mesoderm, notochord, upper blastopore lip	in situ hybridization
Belyaeva OV et al. (2012) Assay Paper	laevis	1 image	NF stage 14	notochord	in situ hybridization
G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus. Paper	laevis	1 image	NF stage 17 to NF stage 18	axial mesoderm, notochord	in situ hybridization
TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: a new link in the FGF/BMP regulatory network. Paper	laevis	1 image	NF stage 10 to NF stage 10.25	upper blastopore lip	in situ hybridization
Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organ... Paper	laevis	1 image	NF stage 14	notochord	in situ hybridization
A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. Paper	laevis	2 images	NF stage 20 to NF stage 35 and 36	endoderm, foregut, gall bladder primordium, lung primordium, notochord	in situ hybridization

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