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Fig. 5. Comparison of XHox11 and XHox11L2 expression in the spinal
cord and brain. A: At stage 23, XHox11 is expressed weakly in a specific
dorsolateral region of the spinal cord. B: XHox11L2 is also expressed in a
dorsolateral region of the spinal cord at stage 25. It is more abundant and
widespread than XHox11. C,D: XHox11L2 expression is maintained in the
spinal cord of stage 30 (C) and 37 (D) embryos. During this time, the
staining moves from a dorsolateral to a dorsal position. E,F: XHox11
transcripts are detected in a dorsolateral region of the hindbrain overlying
the otic vesicle. At stage 30 (E), the staining is located toward the
periphery of the spinal cord, while by stage 37 (F) it has migrated toward
the center. G,H: XHox11L2 is also detected in a region of the hindbrain. G:
Stage 30 embryo showing expression at the outer margin of the brain. H:
By stage 37, XHox11L2 staining has begun to move medially. O, otic
vesicle; V, trigeminal nerve; VIII, acoustic nerve. |
