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Gene/Clone	Species	Stage	Anatomy Item	Experimenter
otx2	xenopus		embryo [+] pronephric nephrostome,pronephric duct,animal blastomere,animal hemisphere,germ plasm,vegetal blastomere,vegetal hemisphere,pronephric nephron,late proximal tubule,early distal tubule,early proximal tubule,late distal tubule,glomus,pronephric sinus,pronephric kidney,primary germ layer,blastomere,embryonic structure,podocyte,early embryonic cell,animal pole,pronephric tubule,vegetal pole,glomeral nexus,proximal tubule,distal tubule,proximal tubule branch,coelom,glomerular mesangial cell,glomerular epithelial cell,germinal granule,prime meridian,Roux spot,fasciculated network of fibrils,germinal vesicle,mitochondrial cloud,oocyte cortex,ooplasm,ring structure,subcortical cytoplasm,vegetal cortex,wedge region,yolk platelet,anatomical group,anatomical region,anatomical space,animal blastomere,blastomere D1,blastomere D1.1,blastomere D1.1.1,blastomere D1.1.2,blastomere D1.2,blastomere D1.2.1,blastomere D1.2.2,blastomere D2,blastomere D2.1,blastomere D2.1.1,blastomere D2.1.2,blastomere D2.2,blastomere D2.2.1,blastomere D2.2.2,blastomere V1,blastomere V1.1,blastomere V1.1.1,blastomere V1.1.2,blastomere V1.2,blastomere V1.2.1,blastomere V1.2.2,blastomere V2,blastomere V2.1,blastomere V2.1.1,blastomere V2.1.2,blastomere V2.2,blastomere V2.2.1,blastomere V2.2.2,egg,embryonic structure,glomeral nexus,mesonephric duct,multicellular anatomical structure,oocyte,polar body,primary oogonium,primary spermatogonium,primordial germ cell,process,secondary oogonium,secondary spermatogonium,spermatid,spermatocyte,spermatozoon,vegetal blastomere

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Expression summary for otx2

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Experiment	Species	Images	Stages	Anatomy	Assay
Cooperation of intrinsic and extrinsic signals in the elaboration of regional identity in the posterior cerebral cortex.	laevis	1 image	NF stage 33 and 34	brain, forebrain, midbrain	immunohistochemistry
Yamamoto A et al. (2005) Assay Paper	laevis	2 images	NF stage 11.5 to NF stage 28	ectoderm, endomesoderm, forebrain, pre-chordal neural plate	in situ hybridization
Satow R et al. (2002) Assay Paper	laevis	1 image	NF stage 18	pre-chordal neural plate	in situ hybridization
Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin. Paper	laevis	1 image	NF stage 14	anterior placodal area, optic field, pre-chordal neural plate, preplacodal ectoderm	in situ hybridization
Louie SH et al. (2009) Assay Paper	laevis	1 image	NF stage 11	upper blastopore lip	in situ hybridization
Belyaeva OV et al. (2012) Assay Paper	laevis	2 images	NF stage 14 to NF stage 20	brain, eye primordium, forebrain, optic vesicle	in situ hybridization
Szenker E et al. (2012) Assay Paper	laevis	1 image	NF stage 10 to NF stage 22	animal hemisphere, cement gland primordium, diencephalon, dorsal marginal zone, neuroectoderm, [+] olfactory placode, optic vesicle	in situ hybridization
Nicetto D et al. (2013) Assay Paper	laevis	1 image	NF stage 20	neural plate, neuroectoderm, optic vesicle, stomodeal-hypophyseal primordium	in situ hybridization
Cizelsky W et al. (2013) Assay Paper	laevis	1 image	NF stage 32	optic vesicle, retina	in situ hybridization
De Marco N et al. (2011) Assay Paper	laevis	5 images	NF stage 19 to NF stage 42	anterior neural ridge, anterior neural tube, anterior placodal area, diencephalon, eye, [+] forebrain, midbrain, optic vesicle, pre-chordal neural plate, presumptive midbrain-hindbrain boundary, retina, retinal outer nuclear layer, telencephalon	in situ hybridization
Acosta H et al. (2015) Assay Paper	laevis	5 images	NF stage 13 to NF stage 15	eye primordium, optic field, pre-chordal neural plate, pre-chordal neural plate border	in situ hybridization
Fredieu JR et al. (1997) Assay Paper	laevis	1 image	NF stage 32	midbrain	in situ hybridization
Zhang S et al. (2014) Assay Paper	tropicalis	1 image	NF stage 17 to NF stage 35 and 36	anterior neural tube, eye, forebrain	in situ hybridization
Zhang S et al. (2014) Assay Paper	laevis	1 image	NF stage 17 to NF stage 35 and 36	eye, forebrain, optic vesicle, retina	in situ hybridization
Fgfr signaling is required as the early eye field forms to promote later patterning and morphogenesis of the eye.	laevis	1 image	NF stage 40	central retina, eye, peripheral retina, retina, retinal inner nuclear layer, [+] retinal neural layer, retinal outer nuclear layer	immunohistochemistry
Overexpression of Xgsk-3 disrupts anterior ectodermal patterning in Xenopus. Paper	laevis	1 image	NF stage 13	pre-chordal neural plate	in situ hybridization
Mechanism of activation of the Formin protein Daam1. Paper	laevis	1 image	NF stage 10.5 to NF stage 14	upper blastopore lip	in situ hybridization
Eroshkin FM et al. (2016) Assay Paper	laevis	2 images	NF stage 14 to NF stage 15	eye primordium, optic field, pre-chordal neural plate, pre-chordal neural plate border	in situ hybridization
Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway. Paper	laevis	1 image	NF stage 33 and 34	eye, midbrain	in situ hybridization
Expression of Xfz3, a Xenopus frizzled family member, is restricted to the early nervous system. Paper	laevis	1 image	NF stage 28	forebrain	in situ hybridization

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