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Gene/Clone	Species	Stage	Anatomy Item	Experimenter
otx2	xenopus		eye [+] lower eyelid,lens,retina,ciliary marginal zone,cornea,globe,conjunctiva,sclera,iris,ciliary body,optic nerve,lens placode,pupil,choroid fissure,photoreceptor layer,retinal neural layer,retinal pigmented epithelium,retinal outer plexiform layer,retinal outer nuclear layer,optic fiber layer,retinal inner nuclear layer,inner limiting membrane,retinal ganglion cell layer,outer limiting membrane,retinal inner plexiform layer,lens epithelium,lens transitional zone,lens fiber cell mass,horizontal cell,bipolar neuron,amacrine cell,retinal ganglion cell,eye photoreceptor cell,retinal stem cell region,retinal progenitor cell region,central retina,peripheral retina,choroid,retinal stem cell,retinal progenitor cell,Muller cell,optic disc,lens epithelium,lens fiber cell mass,lens transitional zone,lens

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Expression summary for otx2

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Experiment	Species	Images	Stages	Anatomy	Assay
Dicer inactivation causes heterochronic retinogenesis in Xenopus laevis.	laevis	1 image	NF stage 42	lens, lens fiber cell mass, retina, retinal inner nuclear layer, retinal outer nuclear layer	immunohistochemistry
Elkins MB and Henry JJ (2006) Assay Paper	laevis	1 image	NF stage 35 and 36	retina, retinal neural layer	in situ hybridization
Xenopus SMOC-1 Inhibits bone morphogenetic protein signaling downstream of receptor binding and is essential for postgastrula... Paper	laevis	1 image	NF stage 32	eye	in situ hybridization
Dynamic in vivo binding of transcription factors to cis-regulatory modules of cer and gsc in the stepwise formation of the Sp... Paper	laevis	1 image	NF stage 26	retina	immunohistochemistry
Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis. Paper	laevis	1 image	NF stage 22	eye, retina	in situ hybridization
Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis. Paper	laevis	1 image	NF stage 29 and 30	eye, retina	in situ hybridization
Identification of otx2 target genes and restrictions in ectodermal competence during Xenopus cement gland formation. Paper	laevis	1 image	NF stage 15	eye	in situ hybridization
Essential role of CREB family proteins during Xenopus embryogenesis. Paper	laevis	1 image	NF stage 28	eye	in situ hybridization
Regulation of eye development by frizzled signaling in Xenopus. Paper	laevis	1 image	NF stage 28	eye	in situ hybridization
Perron M et al. (1998) Assay Paper	laevis	1 image	NF stage 40	eye, retina, retinal inner nuclear layer	in situ hybridization
Bugner V et al. (2011) Assay Paper	laevis	1 image	NF stage 23	eye	in situ hybridization
Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann''s organizer. Paper	laevis	1 image	NF stage 29 and 30	eye	in situ hybridization
Dystroglycan is required for proper retinal layering. Paper	laevis	1 image	NF stage 25 to NF stage 28	eye	in situ hybridization
Dystroglycan is required for proper retinal layering. Paper	laevis	1 image	NF stage 45	eye, retina, retinal neural layer, retinal outer nuclear layer	in situ hybridization
Henry JJ et al. (2002) Assay Paper	laevis	1 image	NF stage 14 to NF stage 32	lens	in situ hybridization
Separation of neural induction and neurulation in Xenopus. Paper	laevis	1 image	NF stage 35 and 36	eye	in situ hybridization
Misexpression of Polycomb-group proteins in Xenopus alters anterior neural development and represses neural target genes. Paper	laevis	1 image	NF stage 19 to NF stage 26	eye	in situ hybridization
Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and die... Paper	tropicalis	1 image	NF stage 24	eye, retina	in situ hybridization
Cizelsky W et al. (2013) Assay Paper	laevis	1 image	NF stage 32	retina	in situ hybridization
De Marco N et al. (2011) Assay Paper	laevis	4 images	NF stage 19 to NF stage 42	eye, retina, retinal outer nuclear layer	in situ hybridization

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